Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | CCL2 | P13500 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1276091 | 0.84 | HTR2A (0.50) | CYP2D6HTR2ABRD4CCL2KDM4E | |
| SCHEMBL31099344 | 0.84 | HTR2A (0.50) | CYP2D6HTR2ABRD4CCL2KDM4E | |
| SCHEMBL1536632 | 0.78 | HTR2A (0.42) | CYP2D6HTR2ABRD4CCL2KDM4E | |
| SCHEMBL8522211 | 0.77 | CYP2D6 (0.50) | CYP2D6HTR2ABRD4CCL2KDM4E | |
| SCHEMBL14690861 | 0.74 | HTR2A (0.42) | CYP2D6HTR2ABRD4CCL2KDM4E | |
| SCHEMBL12573963 | 0.74 | BRD4 (0.55) | CYP2D6HTR2ABRD4CCL2KDM4E | |
| SCHEMBL7334568 | 0.74 | HTR2A (0.47) | CYP2D6HTR2ABRD4CCL2KDM4E | |
| Alcohol SCHEMBL9893729 | 0.74 | HTR2A (0.47) | CYP2D6HTR2ABRD4CCL2KDM4E | |
| SCHEMBL4235527 | 0.74 | HTR2A (0.42) | CYP2D6HTR2ABRD4CCL2KDM4E | |
| SCHEMBL6512485 | 0.74 | BRD4 (0.55) | CYP2D6HTR2ABRD4CCL2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736071-B1 | DERIVATIVES OF HYDROXYNAPHTHALENECARBOXYLIC ACID AND AZO COLORANTS MADE THEREFROM | MILLIKEN & CO (US) | 2001-04-18 | — | — | EP | claimed |
| EP-3630759-B1 | COMPOUNDS USEFUL AS ION CHANNEL INHIBITORS FOR THE TREATMENT OF CANCER | CENTRE NAT RECH SCIENT (FR) | 2024-05-01 | — | — | EP | disclosed |
| US-11932638-B2 | Ion channel inhibitor compounds for cancer treatment | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFQUE (FR) | 2024-03-19 | — | — | US | disclosed |
| US-20210009581-A1 | ION CHANNEL INHIBITOR COMPOUNDS FOR CANCER TREATMENT | CHU NANTES (FR) | 2021-01-14 | — | — | US | disclosed |
| US-20200147086-A1 | INHIBITORS OF NUCLEOTIDYLTRANSFERASE SUPERFAMILY ENZYMES AS ANTIBIOTICS | SAINT LOUIS UNIVERSITY (US) | 2020-05-14 | — | — | US | disclosed |
| EP-3630759-A1 | ION CHANNEL INHIBITOR COMPOUNDS FOR CANCER TREATMENT | Centre National De La Recherche Scientifique (FR) | 2020-04-08 | — | — | EP | disclosed |
| CN-106967023-B | A kind of preparation method of β -2,6- dideoxy sugar aryl-C- glucosides | 华东师范大学 | 2019-09-10 | — | — | CN | disclosed |
| WO-2018215557-A1 | ION CHANNEL INHIBITOR COMPOUNDS FOR CANCER TREATMENT | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-11-29 | — | — | WO | disclosed |
| CN-107108774-A | Ultra-violet solidified fluid composition, the uv-curing type ink jet ink using it, ultraviolet hardening wet type electrophotographic liquid developer, ultraviolet hardening electrostatic inkjet ink and image forming method | 佳能株式会社 | 2017-08-29 | — | — | CN | disclosed |
| CN-106967023-A | A kind of preparation method of the sugared aryl C glucosides of the dideoxies of β 2,6 | 华东师范大学 | 2017-07-21 | — | — | CN | disclosed |
| CN-105793324-A | Stabilizer for thiol-ene compositions | 湛新比利时股份有限公司 | 2016-07-20 | — | — | CN | disclosed |
| WO-2003053386-A1 | ENHANCED COLOUR DEPOSITION FOR HAIR WITH SEQUESTERING AGENTS | UNILEVER PLC (GB) | 2003-07-03 | — | — | WO | disclosed |
| EP-1200135-A1 | MONITORING METHOD FOR STERILIZATION WITH ETHYLENE OXIDE | Patel, Gordhanbhai N. (US) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001010471-A1 | DOSIMETER FOR STERILIZATION WITH ETHYLENE OXIDE | PATEL GORDHANBHAI N (US) | 2001-02-15 | — | — | WO | disclosed |
| EP-0250201-A2 | Photographic silver halide element and process | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1987-12-23 | — | — | EP | disclosed |
| US-3985566-A | Photosensitive crosslinkable 1-carbonyloxy-1H-naphthalene-2-one polymers and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11932638-B2 | Ion channel inhibitor compounds for cancer treatment | CACNA1E, KCNA1, KCNT1 | CYP2D6 1351/4885HTR2A 2259/4885BRD4 855/4885 |
| US-20200147086-A1 | INHIBITORS OF NUCLEOTIDYLTRANSFERASE SUPERFAMILY ENZYMES AS ANTIBIOTICS | DNTT, APRT, RNGTT | CYP2D6 2948/4885HTR2A 4662/4885BRD4 1640/4885 |
| US-20210009581-A1 | ION CHANNEL INHIBITOR COMPOUNDS FOR CANCER TREATMENT | CACNA1E, KCNA1, KCNT1 | CYP2D6 1351/4885HTR2A 2259/4885BRD4 855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.