Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 2/20 | 0.38 |
| ▸ | MGMT | P16455 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28503979 | 0.69 | HRH1 (0.39) | L3MBTL1MAOAMAOBHRH1LMNA | |
| SCHEMBL884890 | 0.66 | KDM1A (0.39) | L3MBTL1LMNASMN1; SMN2KDM4EMAPT | |
| SCHEMBL7915833 | 0.65 | MAOA (0.50) | L3MBTL1MAOAMAOBHRH1LMNA | |
| SCHEMBL29452029 | 0.65 | MAOA (0.50) | L3MBTL1MAOAMAOBHRH1LMNA | |
| SCHEMBL31617176 | 0.65 | HRH1 (0.38) | L3MBTL1MAOAMAOBHRH1MGMT | |
| SCHEMBL20069016 | 0.63 | SLC6A4 (0.44) | L3MBTL1MAOAMAOBHRH1LMNA | |
| SCHEMBL9601979 | 0.62 | HRH1 (0.38) | L3MBTL1MAOAMAOBHRH1MGMT | |
| SCHEMBL28270390 | 0.62 | HRH1 (0.44) | L3MBTL1MAOAMAOBHRH1LMNA | |
| SCHEMBL5822763 | 0.61 | — | — | |
| SCHEMBL23500896 | 0.60 | HRH1 (0.39) | L3MBTL1MAOAMAOBHRH1MGMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009063240-A1 | 2,4-DIAMINOPYRIMIDINE DERIVATIVES USEFUL AS INHIBITORS OF AURORA KINASE | ARROW THERAPEUTICS LIMITED (GB) | 2009-05-22 | — | — | WO | disclosed |