SCHEMBL398487

SCHEMBL398487

O=C(O)c1c[c]cc(C(=O)O)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.45
TP53 P04637 2/20 0.45
CA12 O43570 5/20 0.43
CA1 P00915 5/20 0.43
CA2 P00918 5/20 0.43
CA9 Q16790 5/20 0.43
CA7 P43166 4/20 0.43
CA14 Q9ULX7 4/20 0.43
LCK P06239 1/20 0.42
FYN P06241 1/20 0.42
CA6 P23280 4/20 0.42
TPMT P51580 3/20 0.42
CA4 P22748 3/20 0.42
KDM4E B2RXH2 2/20 0.42
MAPT P10636 2/20 0.42
CA3 P07451 2/20 0.42
CA5A P35218 2/20 0.42
CA5B Q9Y2D0 2/20 0.42
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21268373 0.88 DHODH (0.46) TSHRTP53CA12CA1CA2
SCHEMBL10462446 0.85 TPMT (0.58) TSHRTP53CA12CA1CA2
SCHEMBL5406065 0.85 CA12 (0.54) TSHRTP53CA12CA1CA2
SCHEMBL7522303 0.83 TPMT (0.56) TSHRTP53CA12CA1CA2
SCHEMBL28359997 0.83 HCAR1 (0.48) TSHRTP53CA12CA1CA2
SCHEMBL445788 0.83 KDM4E (0.47) TSHRTP53CA12CA1CA2
SCHEMBL6199906 0.83 TSHR (0.36) TSHRTP53CA12CA1CA2
SCHEMBL16960725 0.83 TPMT (0.48) TSHRTP53CA12CA1CA2
SCHEMBL7522038 0.83 POLB (0.47) TSHRTP53CA12CA1CA2
SCHEMBL21268393 0.82 TSHR (0.47) TSHRCA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 957 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118344695-A Hydroxyl-enriched cycloolefin copolymer long afterglow material and application thereof 重庆理工大学 2024-07-16 CN claimed
CN-118165288-A Continuous microfluidic channel synthesis method of hydrogen production catalyst 山东金德新材料有限公司 2024-06-11 CN claimed
CN-117943126-B Preparation for environmental deodorization and preparation method thereof 广州然益生物环保科技有限公司 2024-06-07 CN claimed
CN-118022838-A Preparation capable of degrading volatile organic compound gas and preparation method thereof 广州然益生物环保科技有限公司 2024-05-14 CN claimed
CN-117943126-A Preparation for environmental deodorization and preparation method thereof 广州然益生物环保科技有限公司 2024-04-30 CN claimed
CN-117924658-A Preparation method of elastic polyurethane material 惠州市远安新材料有限公司 2024-04-26 CN claimed
CN-115196617-B Preparation method of boron doped porous carbon rod-shaped material 亳州市亚珠新材料有限公司 2023-12-19 CN claimed
CN-115847629-B Efficient energy-saving environment-friendly quartz ring preparation process 江苏富乐徳石英科技有限公司 2023-09-29 CN claimed
WO-2023168367-A1 QUINOLINE cGAS ANTAGONIST COMPOUNDS IMMUNESENSOR THERAPEUTICS, INC. (US) 2023-09-07 WO claimed
CN-115124490-B Rigid polydentate tetracarboxylic acid organic ligand with thiadiazole functional group for preparing metal organic framework and preparation method thereof 江西理工大学 2023-08-01 CN claimed
US-5312723-A Contains indoaniline dye with at least five sulfonic and/or carboxylic acid groups FUJI PHOTO FILM CO., LTD. (JP) 1994-05-17 US claimed
US-5290536-A Phenyl substituted 2-thiazolyl tetrazolium salt indicators MILES INC. (US) 1994-03-01 US claimed
US-5281263-A Disazo dyes for inks printed paper IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1994-01-25 US claimed
EP-0572419-A1 ANIONIC DISAZO DYES. ZENECA LTD (GB) 1993-12-08 EP claimed
EP-0570888-A1 Silver halide photographic photosensitive materials FUJI PHOTO FILM CO., LTD. (JP) 1993-11-24 EP claimed
US-5177195-A Black, ink jet printing on paper IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1993-01-05 US claimed
US-5147770-A Entitled silver halide photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1992-09-15 US claimed
WO-1992013037-A1 ANIONIC DISAZO DYES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-08-06 WO claimed
EP-0494523-A1 Anionic disazo dyes ZENECA LIMITED (GB) 1992-07-15 EP claimed
EP-0476928-A1 Light-sensitive silver halide photographic material KONICA CORPORATION (JP) 1992-03-25 EP claimed