Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 20/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1006362 | 0.86 | HTR3A (0.47) | HTR3AKCNH2CYP2C19 | |
| Hydrochloric Acid SCHEMBL1005553 | 0.82 | HTR3A (0.69) | HTR3AKCNH2CYP2C19 | |
| SCHEMBL1004466 | 0.81 | HTR3A (0.66) | HTR3AKCNH2CYP2C19 | |
| SCHEMBL1005720 | 0.81 | HTR3A (0.67) | HTR3AKCNH2CYP2C19 | |
| Hydrochloric Acid SCHEMBL1005562 | 0.80 | HTR3A (0.66) | HTR3AKCNH2CYP2C19 | |
| Hydrochloric Acid SCHEMBL1004299 | 0.80 | HTR3A (0.65) | HTR3AKCNH2CYP2C19 | |
| SCHEMBL1004856 | 0.79 | HTR3A (0.46) | HTR3AKCNH2CYP2C19 | |
| SCHEMBL1006786 | 0.79 | HTR3A (0.51) | HTR3AKCNH2CYP2C19 | |
| SCHEMBL1005533 | 0.78 | HTR3A (0.57) | HTR3AKCNH2CYP2C19 | |
| Hydrochloric Acid SCHEMBL1005891 | 0.78 | HTR3A (0.45) | HTR3AKCNH2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2061460-A2 | 2-AMINOBENZOXAZOLE CARBOXAMIDES AS 5HT3 MODULATORS | Albany Molecular Research, Inc. (US) | 2009-05-27 | — | — | EP | disclosed |
| WO-2008019372-A2 | 2-AMINOBENZOXAZOLE CARBOXAMIDES AS 5HT3 MODULATORS | ALBANY MOLECULAR RESEARCH, INC. (US) | 2008-02-14 | — | — | WO | disclosed |