Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | HBB | P68871 | 1/20 | 0.36 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.35 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | TK1 | P04183 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | GAPDH | P04406 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.33 |
| ▸ | TK2 | O00142 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25403682 | 0.87 | MEN1 (0.37) | MEN1USP2POLBKMT2ARNASE1 | |
| SCHEMBL13844473 | 0.78 | PDE4D (0.39) | MEN1USP2POLBKMT2AMAPT | |
| SCHEMBL7942376 | 0.77 | MEN1 (0.61) | MEN1USP2POLBKMT2ARNASE1 | |
| SCHEMBL9002093 | 0.77 | MEN1 (0.61) | MEN1USP2POLBKMT2ARNASE1 | |
| SCHEMBL20983914 | 0.77 | MEN1 (0.61) | MEN1USP2POLBKMT2ARNASE1 | |
| SCHEMBL5080725 | 0.77 | MEN1 (0.61) | MEN1USP2POLBKMT2ARNASE1 | |
| SCHEMBL9002102 | 0.77 | MEN1 (0.61) | MEN1USP2POLBKMT2ARNASE1 | |
| SCHEMBL15841051 | 0.77 | POLB (0.43) | MEN1USP2POLBKMT2ARNASE1 | |
| SCHEMBL16644423 | 0.77 | POLB (0.40) | MEN1USP2POLBKMT2ARNASE1 | |
| SCHEMBL15841050 | 0.77 | POLB (0.42) | MEN1USP2POLBKMT2ARNASE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009058800-A2 | SYNTHESIS OF NUCLEOSIDES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2009-05-07 | — | — | WO | disclosed |
| WO-2009058800-A2 | SYNTHESIS OF NUCLEOSIDES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2009-05-07 | — | — | WO | disclosed |