Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | TET2 | Q6N021 | 6/20 | 0.43 |
| ▸ | TET3 | O43151 | 2/20 | 0.43 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.43 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 2/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2935591 | 1.00 | SMN1; SMN2 (0.50) | SMN1; SMN2LTA4HTET2TET3TET1 | |
| Malic Acid SCHEMBL30388197 | 0.81 | SMN1; SMN2 (0.71) | SMN1; SMN2TET2TET3TET1OR51E2 | |
| SCHEMBL8071224 | 0.80 | SMN1; SMN2 (0.55) | SMN1; SMN2TET2TET3TET1OR51E2 | |
| SCHEMBL4410670 | 0.80 | SMN1; SMN2 (0.55) | SMN1; SMN2TET2TET3TET1OR51E2 | |
| SCHEMBL8060386 | 0.80 | SMN1; SMN2 (0.55) | SMN1; SMN2TET2TET3TET1OR51E2 | |
| SCHEMBL8060390 | 0.80 | SMN1; SMN2 (0.55) | SMN1; SMN2TET2TET3TET1OR51E2 | |
| SCHEMBL434919 | 0.78 | SLC7A5 (0.58) | LTA4HSLC7A5SLC1A3SLC1A2SLC1A1 | |
| Malic Acid SCHEMBL21145201 | 0.78 | SMN1; SMN2 (0.75) | SMN1; SMN2TET2TET3TET1OR51E2 | |
| Malic Acid SCHEMBL21145198 | 0.78 | SMN1; SMN2 (0.75) | SMN1; SMN2TET2TET3TET1OR51E2 | |
| SCHEMBL21585639 | 0.78 | SLC7A5 (0.58) | LTA4HSLC7A5SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009055779-A1 | A METHOD FOR REVERSAL OF BACTERIAL RESISTANCE TO METALLO-B-LACTAMASE ANTIBIOTICS AND VANCOMYCIN | REDOX PHARMACEUTICAL CORPORATION (US) | 2009-04-30 | — | — | WO | disclosed |