Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | TET2 | Q6N021 | 6/20 | 0.46 |
| ▸ | TET3 | O43151 | 2/20 | 0.46 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.46 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | KDM4A | O75164 | 2/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.39 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8060390 | 1.00 | SMN1; SMN2 (0.55) | SMN1; SMN2TET2TET3TET1OR51E2 | |
| SCHEMBL8071224 | 1.00 | SMN1; SMN2 (0.55) | SMN1; SMN2TET2TET3TET1OR51E2 | |
| SCHEMBL4410670 | 0.84 | SMN1; SMN2 (0.55) | SMN1; SMN2TET2TET3TET1OR51E2 | |
| Ammonia Solution, Strong SCHEMBL5697795 | 0.82 | SMN1; SMN2 (0.52) | SMN1; SMN2TET2TET3TET1OR51E2 | |
| SCHEMBL2059417 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2TET2TET3TET1OR51E2 | |
| SCHEMBL3985265 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2TET2TET3TET1OR51E2 | |
| SCHEMBL2935591 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2TET2TET3TET1OR51E2 | |
| SCHEMBL10308337 | 0.79 | ALDH1A1 (0.32) | SMN1; SMN2TP53ALDH1A1TDP1 | |
| SCHEMBL10308563 | 0.79 | ALDH1A1 (0.38) | SMN1; SMN2TP53ALDH1A1TDP1 | |
| SCHEMBL10308606 | 0.79 | ALDH1A1 (0.38) | SMN1; SMN2TP53ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620857-B1 | SYNTHESIS OF HOMOCHIRAL 2-HYDROXY ACIDS | GENZYME LTD (GB) | 2000-08-02 | — | — | EP | disclosed |
| US-5686275-A | LACTATE DEHYDROGENASE | GENZYME LTD. (GB) | 1997-11-11 | — | — | US | disclosed |
| EP-0620857-A1 | SYNTHESIS OF HOMOCHIRAL 2-HYDROXY ACIDS | Genzyme Limited (GB) | 1994-10-26 | — | — | EP | disclosed |
| WO-1993013215-A1 | SYNTHESIS OF HOMOCHIRAL 2-HYDROXY ACIDS | GENZYME LIMITED (GB) | 1993-07-08 | — | — | WO | disclosed |