Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.49 |
| ▸ | PARG | Q86W56 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL398534 | 1.00 | MAPT (0.54) | MAPTSMN1; SMN2KDM4EMEN1NPC1 | |
| SCHEMBL398494 | 0.85 | AKR1C3 (0.53) | MAPTLMNAAKR1C3HDAC1HDAC3 | |
| SCHEMBL398495 | 0.85 | AKR1C3 (0.53) | MAPTLMNAAKR1C3HDAC1HDAC3 | |
| SCHEMBL398264 | 0.83 | AKR1C3 (0.50) | MAPTSMN1; SMN2KDM4EMEN1NPC1 | |
| SCHEMBL398263 | 0.83 | AKR1C3 (0.50) | MAPTSMN1; SMN2KDM4EMEN1NPC1 | |
| SCHEMBL396101 | 0.81 | AKR1C3 (0.49) | AKR1C3HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL396989 | 0.81 | HDAC1 (0.60) | MAPTMEN1HPGDKMT2AAKR1C3 | |
| SCHEMBL396988 | 0.81 | HDAC1 (0.60) | MAPTMEN1HPGDKMT2AAKR1C3 | |
| SCHEMBL392886 | 0.81 | AKR1C3 (0.49) | MAPTLMNAKMT2AAKR1C3HDAC1 | |
| SCHEMBL396102 | 0.81 | AKR1C3 (0.49) | AKR1C3HDAC1HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101332-B2 | Negative-working lithographic printing plate precursor and method of lithographic printing using same | FUJIFILM CORPORATION (JP) | 2012-01-24 | — | — | US | disclosed |
| US-20090246688-A1 | NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING USING SAME | FUJIFILM CORPORATION (JP) | 2009-10-01 | — | — | US | disclosed |