Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | SNCA | P37840 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9222365 | 0.85 | ALDH1A1 (0.46) | CA12CA9ALDH1A1ALOX15TDP1 | |
| SCHEMBL3240394 | 0.81 | ALDH1A1 (0.57) | CA12CA9TTRALDH1A1ALOX15 | |
| SCHEMBL29761562 | 0.81 | ALDH1A1 (0.57) | CA12CA9TTRALDH1A1ALOX15 | |
| SCHEMBL14210874 | 0.79 | SMN1; SMN2 (0.46) | CA12CA9ALDH1A1ALOX15TDP1 | |
| SCHEMBL810816 | 0.79 | TDP1 (0.50) | CA12CA9TTRALDH1A1ALOX15 | |
| SCHEMBL24557845 | 0.79 | ALDH1A1 (0.49) | CA12CA9ALDH1A1ALOX15TDP1 | |
| SCHEMBL22382466 | 0.79 | TTR (0.42) | CA12CA9TTRALDH1A1ALOX15 | |
| SCHEMBL24557843 | 0.79 | TDP1 (0.43) | CA12CA9ALDH1A1ALOX15TDP1 | |
| SCHEMBL19438425 | 0.77 | AR (0.41) | CA12CA9TTRALDH1A1ALOX15 | |
| SCHEMBL17379066 | 0.76 | ALDH1A1 (0.50) | CA12CA9ALDH1A1ALOX15TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116102575-B | Cyclic 2-aminopyrimidine compound and application thereof | 暨南大学 | 2025-01-17 | — | — | CN | disclosed |
| WO-2023082052-A1 | CYCLIC 2-AMINOPYRIMIDINE COMPOUND AND APPLICATION THEREOF | 暨南大学 | 2023-05-19 | — | — | WO | disclosed |
| CN-116102575-A | Cyclic 2-aminopyrimidine compound and application thereof | 暨南大学 | 2023-05-12 | — | — | CN | disclosed |
| US-7541478-B2 | Coumarin derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-02 | — | — | US | disclosed |
| US-7541478-B2 | Coumarin derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-02 | — | — | US | disclosed |
| US-7541478-B2 | Coumarin derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-02 | — | — | US | disclosed |
| US-20070197636-A1 | Coumarin Derivative And Use Thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-08-23 | — | — | US | disclosed |
| US-20070197636-A1 | Coumarin Derivative And Use Thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-08-23 | — | — | US | disclosed |
| US-20070197636-A1 | Coumarin Derivative And Use Thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-08-23 | — | — | US | disclosed |
| CN-1950352-A | Coumarin derivative and use thereof | TAKEDA PHARMACEUTICAL (JP) | 2007-04-18 | — | — | CN | disclosed |
| EP-1720850-A1 | COUMARIN DERIVATIVE AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005082879-A1 | COUMARIN DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-09-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197636-A1 | Coumarin Derivative And Use Thereof | CBR3, HCCS, CBR1 | CA12 340/4885CA9 767/4885TTR 4603/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.