Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 1/20 | 0.32 |
| ▸ | F3 | P13726 | 1/20 | 0.32 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.32 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.30 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3079269 | 0.89 | SHMT2 (0.38) | F7F3SHMT2 | |
| SCHEMBL3079834 | 0.80 | NR1H2 (0.41) | SHMT2NR1H2 | |
| SCHEMBL3089693 | 0.80 | NR1H2 (0.41) | SHMT2NR1H2 | |
| SCHEMBL3079034 | 0.80 | NR1H2 (0.41) | SHMT2NR1H2 | |
| SCHEMBL3074571 | 0.80 | NR1H2 (0.41) | SHMT2NR1H2 | |
| SCHEMBL3074566 | 0.80 | NR1H2 (0.41) | SHMT2NR1H2 | |
| SCHEMBL8224134 | 0.80 | NR1H2 (0.41) | SHMT2NR1H2 | |
| SCHEMBL11355508 | 0.80 | NR1H2 (0.41) | SHMT2NR1H2 | |
| SCHEMBL3091021 | 0.80 | SHMT2 (0.37) | SHMT2 | |
| SCHEMBL3073601 | 0.75 | TDP1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2061756-A2 | 2-AMINOCARBONYLPHENYLAMINO-2-PHENILACETAMIDES AS FACTOR VIIA INHIBITORS USEFUL AS ANTICOAGULANTS | Brystol-Myers Squibb Company (US) | 2009-05-27 | — | — | EP | disclosed |
| WO-2007146719-A2 | 2-AMINOCARBONYLPHENYLAMINO-2-PHENYLACETAMIDES AS FACTOR VIIA INHIBITORS USEFUL AS ANTICOAGULANTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-12-21 | — | — | WO | disclosed |