⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4400038 | 1.00 | — | — | |
| SCHEMBL18523070 | 0.87 | — | — | |
| SCHEMBL15687773 | 0.84 | — | — | |
| SCHEMBL14169375 | 0.84 | — | — | |
| SCHEMBL13528788 | 0.84 | — | — | |
| SCHEMBL19538675 | 0.84 | — | — | |
| SCHEMBL3992933 | 0.83 | — | — | |
| SCHEMBL764242 | 0.83 | — | — | |
| SCHEMBL515191 | 0.82 | KDM4E (0.52) | — | |
| SCHEMBL12409488 | 0.82 | KDM4E (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10322112-B2 | Compound combinations for attenuation of bacterial virulence | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2019-06-18 | — | — | US | disclosed |
| US-20170231962-A1 | Compound Combinations for Attenuation of Bacterial Virulence | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-08-17 | — | — | US | disclosed |
| US-9078461-B2 | Processing biomass | XYLECO, INC. (US) | 2015-07-14 | — | — | US | disclosed |
| US-9078461-B2 | Processing biomass | XYLECO, INC. (US) | 2015-07-14 | — | — | US | disclosed |
| US-20130266556-A9 | PROCESSING BIOMASS | XYLECO, INC. (US) | 2013-10-10 | — | — | US | disclosed |
| US-20130266556-A9 | PROCESSING BIOMASS | XYLECO, INC. (US) | 2013-10-10 | — | — | US | disclosed |
| US-20110081336-A1 | PROCESSING BIOMASS | XYLECO, INC. (US) | 2011-04-07 | — | — | US | disclosed |
| US-20110081336-A1 | PROCESSING BIOMASS | XYLECO, INC. (US) | 2011-04-07 | — | — | US | disclosed |
| US-20090257995-A1 | HARMFUL BACTERIUM CONTROL AGENT CONTAINING BACILLUS THURINGIENSIS | IDEMITSU KOSAN CO., LTD. (JP) | 2009-10-15 | — | — | US | disclosed |
| US-7537906-B2 | Apoptosis inducer and method of screening for a substance inhibiting acylated homoserine lactone | Nomura, Nobuhiko (JP) | 2009-05-26 | — | — | US | disclosed |
| CN-101309696-A | Harmful bacterium control agent containing bacillus thuringiensis | IDEMITSU KOSAN CO (JP) | 2008-11-19 | — | — | CN | disclosed |
| EP-1967196-A1 | HARMFUL BACTERIUM CONTROL AGENT CONTAINING BACILLUS THURINGIENSIS | Idemitsu Kosan Co., Ltd. (JP) | 2008-09-10 | — | — | EP | disclosed |
| US-20040229944-A1 | Apoptosis inducer and method of screening for a substance inhibiting acylated homoserine lactone | NIPPON SHOKUBAI CO., LTD. (JP) | 2004-11-18 | — | — | US | disclosed |
| EP-1442742-A1 | Apoptosis inducer and method of screening for a substance inhibiting acylated homoserine lactone | Nomura, Nobuhiko (JP) | 2004-08-04 | — | — | EP | disclosed |
| EP-0580692-B1 | AUTOINDUCER | UNIV NOTTINGHAM (GB) | 2003-08-13 | — | — | EP | disclosed |
| US-5593827-A | N-(BETA-KETOCAPROYL) HOMOSERINE LACTONE OR ANALOGUE | THE UNIVERSITY OF NOTTINGHAM (GB) | 1997-01-14 | — | — | US | disclosed |
| EP-0580692-A1 | AUTOINDUCER | THE UNIVERSITY OF NOTTINGHAM (GB) | 1994-02-02 | — | — | EP | disclosed |
| WO-1992018614-A1 | AUTOINDUCER | THE UNIVERSITY OF NOTTINGHAM (GB) | 1992-10-29 | — | — | WO | disclosed |