Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3985858 | 1.00 | EPHX1 (0.31) | EPHX1ALDH1A1NR2F2SMN1; SMN2 | |
| SCHEMBL3987562 | 1.00 | EPHX1 (0.31) | EPHX1ALDH1A1NR2F2SMN1; SMN2 | |
| SCHEMBL3981109 | 0.79 | POLB (0.43) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL3984100 | 0.79 | POLB (0.43) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL9963064 | 0.78 | — | — | |
| SCHEMBL3983137 | 0.78 | — | — | |
| SCHEMBL3981794 | 0.74 | FPR3 (0.33) | — | |
| SCHEMBL3984318 | 0.72 | — | — | |
| SCHEMBL3983946 | 0.72 | EPHX1 (0.42) | EPHX1ALDH1A1 | |
| SCHEMBL1660648 | 0.72 | EPHX1 (0.42) | EPHX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1562575-B1 | FUSED CYCLOALKYL AMIDES AND ACIDS AND THEIR THERAPEUTIC APPLICATIONS FOR THE TREATMENT OF I.A. EPILEPSY | ABBOTT LAB (US) | 2009-05-20 | — | — | EP | disclosed |