Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 3/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.41 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.41 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12398 | 0.84 | KDM4E (0.51) | KDM4EALDH1A1HSD17B10NAMPTCNR2 | |
| SCHEMBL3700457 | 0.84 | KDM4E (0.51) | KDM4EALDH1A1HSD17B10NAMPTCNR2 | |
| SCHEMBL3698852 | 0.84 | ALDH1A1 (0.51) | KDM4EALDH1A1HSD17B10NAMPTFAAH | |
| SCHEMBL3706069 | 0.84 | KDM4E (0.51) | KDM4EALDH1A1HSD17B10NAMPTCNR2 | |
| SCHEMBL4191524 | 0.82 | SMYD3 (0.45) | NAMPTTPSAB1TPSD1TPSG1 | |
| SCHEMBL3704195 | 0.82 | NAMPT (0.50) | KDM4EALDH1A1HSD17B10NAMPTCNR2 | |
| SCHEMBL4206159 | 0.80 | KDM1A (0.47) | KDM4EALDH1A1HSD17B10TPSAB1TPSD1 | |
| SCHEMBL4202834 | 0.80 | KDM1A (0.47) | KDM4EALDH1A1HSD17B10TPSAB1TPSD1 | |
| SCHEMBL3707477 | 0.80 | NAMPT (0.49) | KDM4EALDH1A1HSD17B10NAMPTCNR2 | |
| SCHEMBL3704706 | 0.78 | NAMPT (0.55) | KDM4EALDH1A1HSD17B10NAMPTTPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2059516-A1 | PYRIDINE COMPOUNDS FOR TREATING GPR119 RELATED DISORDERS | BIOVITRUM AB (publ) (SE) | 2009-05-20 | — | — | EP | disclosed |
| WO-2008025798-A1 | PYRIDINE COMPOUNDS FOR TREATING GPR119 RELATED DISORDERS | BIOVITRUM AB (PUBL) (SE) | 2008-03-06 | — | — | WO | disclosed |