Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28340972 | 0.85 | ALDH1A1 (0.43) | ALDH1A1ESR1ESR2CYP3A4MAPK1 | |
| SCHEMBL9331418 | 0.85 | ALDH1A1 (0.43) | ALDH1A1ESR1ESR2CYP3A4MAPK1 | |
| SCHEMBL30545314 | 0.85 | ALDH1A1 (0.43) | ALDH1A1ESR1ESR2CYP3A4MAPK1 | |
| SCHEMBL28101262 | 0.82 | MAPK1 (0.50) | ALDH1A1ESR1ESR2CYP3A4MAPK1 | |
| SCHEMBL10541515 | 0.82 | ALDH1A1 (0.47) | ALDH1A1ESR1ESR2CYP3A4MAPK1 | |
| SCHEMBL2221686 | 0.80 | ALDH1A1 (0.39) | ALDH1A1ESR1ESR2CYP3A4MAPK1 | |
| SCHEMBL11429712 | 0.80 | ALDH1A1 (0.39) | ALDH1A1ESR1ESR2CYP3A4MAPK1 | |
| SCHEMBL2199266 | 0.79 | ALDH1A1 (0.54) | ALDH1A1ESR1ESR2CYP3A4MAPK1 | |
| SCHEMBL26923909 | 0.79 | MAPK1 (0.42) | ALDH1A1ESR1ESR2CYP3A4MAPK1 | |
| SCHEMBL22092137 | 0.79 | ALDH1A1 (0.38) | ALDH1A1ESR1ESR2CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7550586-B2 | Phthalocyanines with peripheral siloxane substitution | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2009-06-23 | — | — | US | disclosed |
| US-20050200803-A1 | Phthalocyanines with peripheral siloxane substitution | THE GOVERNMENT OF THE UNITED STATES, AS RESPRESENTED BY THE SECRETARY OF THE NAVY | 2005-09-15 | — | — | US | disclosed |
| US-6933402-B2 | Phthalocyanines with peripheral siloxane substitution | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2005-08-23 | — | — | US | disclosed |
| US-20030092907-A1 | Phthalocyanines with peripheral siloxane substitution | NAVY,U.S.A. AS REPRESENTED BY, THE SECRETARY OF THE | 2003-05-15 | — | — | US | disclosed |
| US-6498249-B1 | Phthalocyanines with peripheral siloxane substitution | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY | 2002-12-24 | — | — | US | disclosed |