Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 15/20 | 0.57 |
| ▸ | CTSS | P25774 | 7/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3890865 | 1.00 | CTSK (0.57) | CTSKCTSSATMCTSLCTSB | |
| SCHEMBL7534074 | 1.00 | CTSK (0.57) | CTSKCTSSATMCTSLCTSB | |
| SCHEMBL2400972 | 0.88 | CTSK (0.56) | CTSKCTSSATMCTSLCTSB | |
| SCHEMBL13446080 | 0.88 | CTSK (0.56) | CTSKCTSSATMCTSLCTSB | |
| SCHEMBL1519855 | 0.87 | PPARG (0.51) | CTSKCTSSATMCTSLCTSB | |
| SCHEMBL1519854 | 0.87 | PPARG (0.51) | CTSKCTSSATMCTSLCTSB | |
| SCHEMBL1519981 | 0.87 | PPARG (0.51) | CTSKCTSSATMCTSLCTSB | |
| SCHEMBL31341263 | 0.87 | CTSK (0.51) | CTSKCTSSCTSLCTSBMEN1 | |
| SCHEMBL762688 | 0.86 | CTSK (0.57) | CTSKCTSSATMCTSLCTSB | |
| SCHEMBL12029033 | 0.86 | CTSK (0.51) | CTSKCTSSATMCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116693447-A | Ketone amide derivative and pharmaceutical application thereof | 成都威斯克生物医药有限公司 | 2023-09-05 | — | — | CN | disclosed |
| US-7553969-B1 | Substituted phenethylamine derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2009-06-30 | — | — | US | disclosed |
| EP-1149843-A1 | SUBSTITUTED PHENETHYLAMINE DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2001-10-31 | — | — | EP | disclosed |
| EP-0665215-A1 | 1,4-Diamino-2,3-dihydroxybutanes | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-08-02 | — | — | EP | disclosed |
| US-5430155-A | Viricides, treatment of AIDS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-07-04 | — | — | US | disclosed |
| US-5294720-A | Viricides | THE DUPONT MERCK PHARMACEUTICAL CO. (US) | 1994-03-15 | — | — | US | disclosed |
| WO-1991018866-A2 | 1,4-DIAMINO-2,3-DIHYDROXYBUTANES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1991-12-12 | — | — | WO | disclosed |