Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fenazaquin SCHEMBL26216 | 0.90 | RAB9A (0.54) | RAB9ANPC1TSHRL3MBTL1CYP1A2 | |
| Fenazaquin SCHEMBL29429249 | 0.90 | RAB9A (0.54) | RAB9ANPC1TSHRL3MBTL1CYP1A2 | |
| Fenazaquin SCHEMBL27889647 | 0.89 | RAB9A (0.52) | RAB9ANPC1TSHRL3MBTL1CYP1A2 | |
| SCHEMBL8547995 | 0.84 | RAB9A (0.52) | RAB9ANPC1TSHRL3MBTL1CYP1A2 | |
| SCHEMBL8547053 | 0.83 | RAB9A (0.51) | RAB9ANPC1TSHRL3MBTL1CYP1A2 | |
| SCHEMBL12722378 | 0.79 | RAB9A (0.52) | RAB9ANPC1TSHRL3MBTL1CYP1A2 | |
| SCHEMBL9430851 | 0.79 | TRPV1 (0.39) | RAB9ANPC1TSHRL3MBTL1CYP1A2 | |
| SCHEMBL19185789 | 0.78 | RAB9A (0.49) | RAB9ANPC1TSHRL3MBTL1CYP1A2 | |
| SCHEMBL8543530 | 0.78 | RAB9A (0.54) | RAB9ANPC1TSHRL3MBTL1CYP1A2 | |
| Hydrochloric Acid SCHEMBL27889646 | 0.76 | RAB9A (0.49) | RAB9ANPC1TSHRL3MBTL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090215859-A1 | Compositions and methods for modulating dhr96 | UTAH, UNIVERSITY OF | 2009-08-27 | — | — | US | disclosed |
| EP-1809761-A4 | COMPOSITIONS AND METHODS FOR MODULATING DHR96 | UNIV UTAH RES FOUND (US) | 2009-03-18 | — | — | EP | disclosed |
| EP-1809761-A2 | COMPOSITIONS AND METHODS FOR MODULATING DHR96 | University of Utah Research Foundation (US) | 2007-07-25 | — | — | EP | disclosed |
| WO-2005069859-A2 | COMPOSITIONS AND METHODS FOR MODULATING DHR96 | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2005-08-04 | — | — | WO | disclosed |