Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA4 | P22748 | 3/20 | 0.44 |
| ▸ | CA6 | P23280 | 3/20 | 0.44 |
| ▸ | CA5A | P35218 | 3/20 | 0.44 |
| ▸ | CA7 | P43166 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.44 |
| ▸ | CASP2 | P42575 | 2/20 | 0.44 |
| ▸ | F13A1 | P00488 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | THPO | P40225 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4807054 | 0.98 | MAPT (0.46) | APPCA12CA2CA4CA6 | |
| SCHEMBL12712074 | 0.92 | MAPT (0.50) | APPCYP1A2CYP2C19MAPTALDH1A1 | |
| SCHEMBL9155154 | 0.92 | APP (0.52) | APPCA12CA2CA9MAPT | |
| SCHEMBL12712070 | 0.92 | MAPT (0.50) | APPCYP1A2CYP2C19MAPTALDH1A1 | |
| SCHEMBL12736723 | 0.90 | APP (0.46) | APPCASP2CYP1A2CYP2C19MAPT | |
| SCHEMBL12736181 | 0.88 | PRSS1 (0.48) | APPMAPTALDH1A1PRSS1MAOB | |
| SCHEMBL457665 | 0.86 | APP (0.50) | APPMAPTALDH1A1PRSS1MAOB | |
| SCHEMBL2024986 | 0.85 | MAPT (0.56) | APPCYP1A2MEN1CYP2C19KMT2A | |
| SCHEMBL11934926 | 0.84 | APP (0.49) | APPMAPTALDH1A1PRSS1MAOB | |
| SCHEMBL5155907 | 0.83 | APP (0.50) | APPCYP1A2MEN1CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1568683-B1 | Secondary, N-alkylaminated para-phenylenediamines, compositions for dyeing keratinic fibres containing them, processes using this compositions and uses thereof | OREAL (FR) | 2009-05-27 | — | — | EP | claimed |
| US-7338536-B2 | N-alkylamino secondary para-phenylenediamine, composition for dyeing keratin fibers comprising such a para-phenylenediamine, processes using this composition and uses thereof | L'OREAL S. A. (FR) | 2008-03-04 | — | — | US | claimed |
| US-20060026772-A1 | N-alkylamino secondary para-phenylenediamine, composition for dyeing keratin fibers comprising such a para-phenylenediamine, processes using this composition and uses thereof | L'OREAL | 2006-02-09 | — | — | US | claimed |
| EP-1568683-A2 | Secondary, N-alkylaminated para-phenylenediamines, compositions for dyeing keratinic fibres containing them, processes using this compositions and uses thereof | L'OREAL (FR) | 2005-08-31 | — | — | EP | claimed |
| EP-1568683-B1 | Secondary, N-alkylaminated para-phenylenediamines, compositions for dyeing keratinic fibres containing them, processes using this compositions and uses thereof | OREAL (FR) | 2009-05-27 | — | — | EP | disclosed |
| US-7338536-B2 | N-alkylamino secondary para-phenylenediamine, composition for dyeing keratin fibers comprising such a para-phenylenediamine, processes using this composition and uses thereof | L'OREAL S. A. (FR) | 2008-03-04 | — | — | US | disclosed |
| US-7338536-B2 | N-alkylamino secondary para-phenylenediamine, composition for dyeing keratin fibers comprising such a para-phenylenediamine, processes using this composition and uses thereof | L'OREAL S. A. (FR) | 2008-03-04 | — | — | US | disclosed |
| EP-1568683-A2 | Secondary, N-alkylaminated para-phenylenediamines, compositions for dyeing keratinic fibres containing them, processes using this compositions and uses thereof | L'OREAL (FR) | 2005-08-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060026772-A1 | N-alkylamino secondary para-phenylenediamine, composition for dyeing keratin fibers comprising such a para-phenylenediamine, processes using this composition and uses thereof | KRT18, CDC73, PRKDC | APP 644/4885CA12 1415/4885CA2 3165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.