Sugi Predict

Sugi Predict / Compounds / SCHEMBL457665

SCHEMBL457665

SCHEMBL457665

NCCCCNc1ccc(N)cc1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ APP P05067 1/20 0.50
▸ PRSS1 P07477 8/20 0.47
▸ F2 P00734 2/20 0.46
▸ PRSS2 P07478 2/20 0.46
▸ PRSS3 P35030 2/20 0.46
▸ TMPRSS6 Q8IU80 2/20 0.46
▸ ST14 Q9Y5Y6 2/20 0.46
▸ MAPT P10636 3/20 0.43
▸ ALDH1A1 P00352 1/20 0.43
▸ GAA P10253 1/20 0.39
▸ MAOA P21397 1/20 0.38
▸ MAOB P27338 1/20 0.38
▸ HRH3 Q9Y5N1 1/20 0.38
▸ STK17B O94768 1/20 0.38
▸ STK17A Q9UEE5 1/20 0.38
▸ HDAC3 O15379 1/20 0.37
▸ HDAC1 Q13547 1/20 0.37
▸ HDAC2 Q92769 1/20 0.37
▸ NCOR2 Q9Y618 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11934926 0.98 APP (0.49) APPPRSS1F2PRSS2PRSS3
SCHEMBL28385928 0.98 APP (0.49) APPPRSS1F2PRSS2PRSS3
SCHEMBL9155154 0.93 APP (0.52) APPPRSS1F2PRSS2PRSS3
SCHEMBL34107 0.91 PRSS1 (0.54) APPPRSS1F2PRSS2PRSS3
SCHEMBL18549015 0.89 PRSS1 (0.55) APPPRSS1F2PRSS2PRSS3
SCHEMBL12712067 0.89 PRSS1 (0.55) APPPRSS1F2PRSS2PRSS3
Hydrochloric Acid SCHEMBL4956812 0.89 PRSS1 (0.55) APPPRSS1F2PRSS2PRSS3
SCHEMBL12736182 0.89 PRSS1 (0.55) APPPRSS1F2PRSS2PRSS3
Hydrochloric Acid SCHEMBL11700281 0.89 PRSS1 (0.55) APPPRSS1F2PRSS2PRSS3
Hydrochloric Acid SCHEMBL4953031 0.86 PRSS1 (0.57) APPPRSS1F2PRSS2PRSS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 213 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030172472-A1 Oxidaton dyeing composition for keratinous fibres comprising an amphoteric polymer with fatty chain L'OREAL S.A. (FR) 2003-09-18 — — US claimed
CN-1248577-A Novel cation type 4-oxyindole, its oxidation dyeing, dyeing composition and dyeing method for keration fibre OREAL (FR) 2000-03-29 — — CN claimed
US-5609649-A Tinctorial composition for keratinous fibers containing oxidation dye precursors and couplers derived from 4-hydroxyindole, and dyeing method using them L'OREAL (FR) 1997-03-11 — — US claimed
CN-1051727-A Use 6-or 7-hydroxy indoxyl derivative as chromogenic reagent, contain the composition of this derivative and the staining of carrying out with said composition OREAL (FR) 1991-05-29 — — CN claimed
CN-118103023-A Retarder composition and dye set comprising same 莱雅公司 2024-05-28 — — CN disclosed
CN-118043027-A Process for dyeing and/or lightening keratin fibres 莱雅公司 2024-05-14 — — CN disclosed
CN-112312883-B Device for dispensing hair coloring products using dye compositions and oxidizing compositions comprising scleroglucan gum 莱雅公司 2024-04-02 — — CN disclosed
CN-117715610-A Composition for simultaneously bleaching and dyeing keratin fibers and method for using same 莱雅公司 2024-03-15 — — CN disclosed
CN-117715615-A Composition comprising at least one oxidation dye, 1, 3-propanediol, at least one alkaline agent and at least one fatty substance 莱雅公司 2024-03-15 — — CN disclosed
CN-117651546-A Oxidation retardant composition 莱雅公司 2024-03-05 — — CN disclosed
CN-117615746-A Dye set 莱雅公司 2024-02-27 — — CN disclosed
CN-117597104-A Combination for dyeing keratin fibres and use thereof 莱雅公司 2024-02-23 — — CN disclosed
CN-1189820-A N-substituted 4-hydroxyindole derivatives and keratin fibre dyeing compsns. containing same OREAL (FR) 1998-08-05 — — CN disclosed
US-5578087-A Dyeing compositions for keratinous fibres based on para-phenylene-diamines, meta-phenylenediamine and benzimidazole derivatives, and dyeing process employing them L'OREAL (FR) 1996-11-26 — — US disclosed
US-5567421-A COLORFAST, WASHFAST, WEATHERPROOF, AND PERSPIRATION RESISTANT HAIR DYE L'OREAL (FR) 1996-10-22 — — US disclosed
US-5542952-A DEVELOPERS THAT FORM STABLE OXIDATION HAIR DYES L'OREAL (FR) 1996-08-06 — — US disclosed
US-5514188-A Oxidation dye composition for keratinous fibres comprising a para-aminophenol, 2-methyl-5-aminophenol and a para-phenylenediamine and/or a bis(phenylalkylenediamine) L'OREAL (FR) 1996-05-07 — — US disclosed
EP-0360644-B1 OXIDATION DYEING COMPOSITION CONTAINING AT LEAST ONE DOUBLE AND AT LEAST ONE SINGLE DYEING BASE, AND DYEING PROCESS MAKING USE OF SUCH A COMPOSITION L'OREAL (FR) 1993-02-17 — — EP disclosed
CN-1051727-A Use 6-or 7-hydroxy indoxyl derivative as chromogenic reagent, contain the composition of this derivative and the staining of carrying out with said composition OREAL (FR) 1991-05-29 — — CN disclosed
US-4566875-A HAIR DYES L'OREAL (FR) 1986-01-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030172472-A1 Oxidaton dyeing composition for keratinous fibres comprising an amphoteric polymer with fatty chain KRT18, MB, MDN1 APP 1168/4885PRSS1 3345/4885F2 1497/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.