Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.40 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.40 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.40 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16153007 | 0.82 | NAALAD2 (0.48) | NAALAD2ALDH1A1MEN1CYP1A2THRB | |
| SCHEMBL19173121 | 0.80 | NAALAD2 (0.39) | NAALAD2ALDH1A1MEN1CYP1A2THRB | |
| SCHEMBL10443837 | 0.78 | ALDH1A1 (0.38) | NAALAD2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL10444118 | 0.78 | NAALAD2 (0.35) | NAALAD2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL5497723 | 0.77 | NAALAD2 (0.44) | NAALAD2ALDH1A1MEN1CYP1A2THRB | |
| SCHEMBL11529406 | 0.75 | NAALAD2 (0.50) | NAALAD2ALDH1A1MEN1CYP1A2THRB | |
| SCHEMBL15100349 | 0.75 | NAALAD2 (0.50) | NAALAD2ALDH1A1MEN1CYP1A2THRB | |
| SCHEMBL120318 | 0.75 | — | — | |
| SCHEMBL28173158 | 0.73 | NAALAD2 (0.41) | NAALAD2ALDH1A1MEN1CYP1A2THRB | |
| SCHEMBL23355141 | 0.72 | HMGCR (0.52) | NAALAD2ALDH1A1FFAR3TSHRHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119365471-A | Novel thiol reducing agents, methods and uses thereof | 苏州佰睿壹生物技术有限公司 | 2025-01-24 | — | — | CN | disclosed |
| EP-2864457-B1 | FRICTION MODIFIER AND THEIR USE IN LUBRICANTS AND FUELS | CASTROL LTD (GB) | 2017-08-16 | — | — | EP | disclosed |
| US-9217117-B2 | Friction modifier and their use in lubricants and fuels | CASTROL LIMITED (GB) | 2015-12-22 | — | — | US | disclosed |
| US-20150218479-A1 | FRICTION MODIFIER AND THEIR USE IN LUBRICANTS AND FUELS | CASTROL LIMITED (GB) | 2015-08-06 | — | — | US | disclosed |
| EP-2864457-A1 | FRICTION MODIFIER AND THEIR USE IN LUBRICANTS AND FUELS | Castrol Limited (GB) | 2015-04-29 | — | — | EP | disclosed |
| WO-2013189675-A1 | FRICTION MODIFIER AND THEIR USE IN LUBRICANTS AND FUELS | CASTROL LIMITED (GB) | 2013-12-27 | — | — | WO | disclosed |
| EP-1694329-A4 | DIAMINE AND IMINODIACETIC ACID HYDROXAMIC ACID DERIVATES | ATON PHARMA INC (US) | 2009-06-03 | — | — | EP | disclosed |
| US-20090023718-A1 | Diamine and Iminodiacetic Acid Hydroxamic Acid Derivatives | ATON PHARMA, INC. (US) | 2009-01-22 | — | — | US | disclosed |
| EP-1694329-A2 | DIAMINE AND IMINODIACETIC ACID HYDROXAMIC ACID DERIVATES | Aton Pharma, Inc. (US) | 2006-08-30 | — | — | EP | disclosed |
| WO-2005053610-A2 | DIAMINE AND IMINODIACETIC ACID HYDROXAMIC ACID DERIVATIVES | ATON PHARMA, INC. (US) | 2005-06-16 | — | — | WO | disclosed |
| US-6759509-B1 | CONJUGATES CONTAINING A TARGETING LIGAND, SUCH AS AN ANTIBODY, A THERAPEUTICALLY ACTIVE DRUG AND A BRANCHED PEPTIDE LINKER | BRISTOL-MYERS SQUIBB COMPANY | 2004-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023718-A1 | Diamine and Iminodiacetic Acid Hydroxamic Acid Derivatives | AADAC, BRDT, HDAC5 | NAALAD2 267/4885ALDH1A1 930/4885MEN1 3081/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.