Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.45 |
| ▸ | RELA | Q04206 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 5/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | ACR | P10323 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3994032 | 0.82 | NPC1 (0.47) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL3989964 | 0.81 | KCNH2 (0.52) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL3993124 | 0.81 | LMNA (0.49) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL3998839 | 0.77 | KCNH2 (0.56) | RARBMAPT | |
| SCHEMBL29350004 | 0.76 | NPC1 (0.59) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL9513551 | 0.76 | NPC1 (0.59) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL9450565 | 0.75 | SMN1; SMN2 (0.58) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL9450554 | 0.75 | SMN1; SMN2 (0.58) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL9450563 | 0.75 | SMN1; SMN2 (0.58) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL9450559 | 0.75 | SMN1; SMN2 (0.58) | LMNANPC1NFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7575788-B2 | functionation of polyvinyl alcohol with 4'-(11,11-diethoxy-undecyloxy)-biphenyl-4-carbonitrile (side-chain precursor) and octanal; sandwiching a liquid crystal layer between two substrates, one of which have above polymer, arranged so that said surface-director alignment layer facing liquid crystal layer | ECSIBEO PPF2 AB (SE) | 2009-08-18 | — | — | US | disclosed |
| US-20070088125-A1 | Polymers for use as alignment layers in liquid crystal devices | ECSIBEO PPF2 AB (SE) | 2007-04-19 | — | — | US | disclosed |