SCHEMBL399574

SCHEMBL399574

C=C1CC(C(=O)O)C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1746024 0.97
Lithium SCHEMBL8040608 0.97
Lithium SCHEMBL9464923 0.82 ABAT (0.35)
SCHEMBL12423753 0.79
SCHEMBL15684113 0.79
SCHEMBL5729035 0.79
SCHEMBL1665954 0.78 GABRP (0.39)
SCHEMBL1030281 0.77 GABRR1 (0.39)
SCHEMBL1030623 0.77 GABRR1 (0.39)
SCHEMBL8413192 0.77 GABRR1 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 552 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4707276-A2 MALT1 MODULATORS AND USES THEREOF Rarefied Biosciences, Inc. (US) 2026-03-11 EP disclosed
EP-4499611-B1 MALT1 MODULATORS AND USES THEREOF RAREFIED BIOSCIENCES INC (US) 2026-02-18 EP disclosed
US-20250326738-A1 MALT1 Modulators and Uses Thereof RAREFIED BIOSCIENCES, INC. (US) 2025-10-23 US disclosed
EP-4634159-A1 SULFOXIMINES AS INHIBITORS OF NAV1.8 Grünenthal GmbH (DE) 2025-10-22 EP disclosed
US-20250221966-A1 RXFP1 AGONISTS BRISTOL MYERS SQUIBB CO (US) 2025-07-10 US disclosed
WO-2025036490-A1 DNA POLYMERASE θ INHIBITOR AND USE THEREOF 海思科医药集团股份有限公司 2025-02-20 WO disclosed
WO-2025026266-A1 COMPOUND AS LPAR1 ANTAGONIST, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF 武汉朗来科技发展有限公司 2025-02-06 WO disclosed
EP-4499611-A1 MALT1 MODULATORS AND USES THEREOF Rarefied Biosciences, Inc. (US) 2025-02-05 EP disclosed
US-20240391926-A1 SPIROINDOLINONE COMPOUNDS AS Kv1.3 POTASSIUM SHAKER CHANNEL BLOCKERS D.E. SHAW RESEARCH, LLC 2024-11-28 US disclosed
CN-119032083-A MALT1 modulators and uses thereof 稀有生物科学股份有限公司 2024-11-26 CN disclosed
US-6683212-B1 N-(1-(2-NAPHTHALENYL)ETHYL)CYCLOBUTANECARBOXAMIDE DERIVATIVES; PLANT DISEASES; CROPS; AGRICULTURE E. I. DU PONT DE NEMOURS AND COMPANY 2004-01-27 US disclosed
US-20030191189-A1 Fungicidal amides BASARAB GREGORY S (US) 2003-10-09 US disclosed
US-6504058-B1 (1(R)-cis)-3-chloro-1,3-dimethyl-N-(1-(2-napthalenyl)ethyl) -cyclobutanecarboxamide and/or isomers, used for controlling plant diseases caused by fungi THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS 2003-01-07 US disclosed
WO-1999031048-A1 FUNGICIDAL AMIDES THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) 1999-06-24 WO disclosed
US-5384072-A Liquid crystals MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1995-01-24 US disclosed
EP-0576450-A1 METHYLENE CYCLOBUTANE DERIVATES MERCK PATENT GmbH (DE) 1994-01-05 EP disclosed
US-5246931-A Triazine-substituted cyclobutane derivatives; viricides; side effect reduction BRISTOL-MYERS SQUIBB COMPANY (US) 1993-09-21 US disclosed
US-5153352-A Viricides and antitumor agent BRISTOL-MYERS SQUIBB COMPANY (US) 1992-10-06 US disclosed
WO-1992016483-A1 METHYLENE CYCLOBUTANE DERIVATES MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1992-10-01 WO disclosed
EP-0366059-A2 Carbocyclic nucleoside analogs BRISTOL-MYERS SQUIBB COMPANY (US) 1990-05-02 EP disclosed