Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 3/20 | 1.00 |
| ▸ | OPRM1 | P35372 | 1/20 | 1.00 |
| ▸ | DRD3 | P35462 | 1/20 | 1.00 |
| ▸ | OPRD1 | P41143 | 1/20 | 1.00 |
| ▸ | BCHE | P06276 | 15/20 | 0.65 |
| ▸ | ACHE | P22303 | 1/20 | 0.65 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tianeptine SCHEMBL29877330 | 1.00 | NR1I2 (1.00) | NR1I2OPRM1DRD3OPRD1BCHE | |
| Tianeptine SCHEMBL49293 | 1.00 | NR1I2 (1.00) | NR1I2OPRM1DRD3OPRD1BCHE | |
| Tianeptine SCHEMBL29470274 | 1.00 | NR1I2 (1.00) | NR1I2OPRM1DRD3OPRD1BCHE | |
| Tianeptine SCHEMBL29930593 | 1.00 | NR1I2 (1.00) | NR1I2OPRM1DRD3OPRD1BCHE | |
| Tianeptine SCHEMBL2894680 | 0.99 | NR1I2 (0.98) | NR1I2OPRM1DRD3OPRD1BCHE | |
| Tianeptine SCHEMBL1231001 | 0.99 | NR1I2 (0.98) | NR1I2OPRM1DRD3OPRD1BCHE | |
| Tianeptine SCHEMBL2897771 | 0.99 | NR1I2 (0.98) | NR1I2OPRM1DRD3OPRD1BCHE | |
| SCHEMBL4262606 | 0.99 | NR1I2 (0.98) | NR1I2OPRM1DRD3OPRD1BCHE | |
| Tianeptine SCHEMBL20338621 | 0.98 | NR1I2 (0.96) | NR1I2OPRM1DRD3OPRD1BCHE | |
| Hydrochloric Acid SCHEMBL22664293 | 0.98 | NR1I2 (0.96) | NR1I2OPRM1DRD3OPRD1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3675838-A1 | LYMPHATIC SYSTEM-DIRECTING LIPID PRODRUGS | Puretecch LYT, Inc. (US) | 2020-07-08 | — | — | EP | disclosed |
| WO-2019046491-A1 | LYMPHATIC SYSTEM-DIRECTING LIPID PRODRUGS | ARIYA THERAPEUTICS, INC. (US) | 2019-03-07 | — | — | WO | disclosed |
| EP-1755614-A4 | COMPOSITIONS AND METHODS FOR TREATMENT OF NEUROPATHIC PAIN, FIBROMYALGIA AND CHRONIC FATIGUE SYNDROME | VELA PHARMACEUTICALS INC (US) | 2009-06-10 | — | — | EP | disclosed |
| EP-1755614-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF NEUROPATHIC PAIN, FIBROMYALGIA AND CHRONIC FATIGUE SYNDROME | Vela Pharmaceuticals Inc. (US) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005099714-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF NEUROPATHIC PAIN, FIBROMYALGIA AND CHRONIC FATIGUE SYNDROME | VELA PHARMACEUTICALS, INC. (US) | 2005-10-27 | — | — | WO | disclosed |