Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3763673 | 0.81 | DRD2 (0.37) | DRD2DRD3HTR2AHTR1A | |
| SCHEMBL444346 | 0.73 | DRD2 (0.43) | DRD2DRD3HTR2AHTR1A | |
| SCHEMBL3754800 | 0.71 | SLC6A2 (0.38) | HTR2AHTR1A | |
| SCHEMBL3766721 | 0.70 | SSTR4 (0.38) | — | |
| SCHEMBL3754892 | 0.69 | SLC6A2 (0.36) | — | |
| SCHEMBL28398541 | 0.69 | DRD2 (0.43) | DRD2DRD3HTR2AHTR1A | |
| SCHEMBL3996423 | 0.68 | SSTR4 (0.39) | — | |
| SCHEMBL3770948 | 0.68 | SLC6A2 (0.35) | HTR2AHTR1A | |
| SCHEMBL1965907 | 0.67 | CYP2A6 (0.40) | — | |
| SCHEMBL1639063 | 0.65 | DRD2 (0.46) | DRD2DRD3HTR2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009071895-A1 | FUSED THIAZOLE AND THIOPHENE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2009-06-11 | — | — | WO | disclosed |