Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11810726 | 0.87 | HPGD (0.47) | ALDH1A1AKR1C3RAB9AHPGDSRD5A2 | |
| SCHEMBL11813950 | 0.87 | TSHR (0.45) | ALDH1A1LMNATDP1CYP1A2CYP3A4 | |
| SCHEMBL15943729 | 0.83 | ALDH1A1 (0.47) | ALDH1A1LMNAAKR1C3RAB9AHPGD | |
| SCHEMBL1764282 | 0.83 | ALDH1A1 (0.47) | ALDH1A1LMNAAKR1C3RAB9AHPGD | |
| SCHEMBL12132313 | 0.81 | ALDH1A1 (0.52) | ALDH1A1LMNATDP1AKR1C3RAB9A | |
| SCHEMBL28618722 | 0.78 | KDM4E (0.50) | ALDH1A1LMNATDP1CYP1A2MAPT | |
| SCHEMBL3992020 | 0.77 | ALDH1A1 (0.41) | ALDH1A1LMNATDP1AKR1C3AKR1C2 | |
| SCHEMBL7801625 | 0.77 | ALDH1A1 (0.39) | ALDH1A1LMNARAB9AHPGDSRD5A2 | |
| SCHEMBL7678288 | 0.75 | ALDH1A1 (0.44) | ALDH1A1LMNATDP1AKR1C3RAB9A | |
| SCHEMBL7676938 | 0.75 | MAPT (0.52) | ALDH1A1LMNARAB9AHPGDSRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009072139-A1 | PROCESS FOR PRODUCING 2-[1-METHYL-5-(4-METHYLBENZOYL)- PYRROL-2- YL]ACETIC ACID OR SALT THEREOF | MATRIX LABORATORIES LIMITED (IN) | 2009-06-11 | — | — | WO | disclosed |
| US-4294760-A | Preparation of 5-(arylcyanohydroxymethyl)-1-loweralkylpyrrole-2-acetic acid derivatives | MCNEILAB, INC. (US) | 1981-10-13 | — | — | US | disclosed |