Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | BCR | P11274 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20945439 | 1.00 | GAA (0.48) | GAANPC1ALDH1A1MAPTNPSR1 | |
| SCHEMBL27952777 | 0.82 | GAA (0.65) | GAANPC1ALDH1A1MAPTNPSR1 | |
| SCHEMBL30487990 | 0.82 | GAA (0.65) | GAANPC1ALDH1A1MAPTNPSR1 | |
| Chloroneb SCHEMBL22739 | 0.78 | GAA (0.64) | GAANPC1ALDH1A1MAPTNPSR1 | |
| SCHEMBL16609990 | 0.75 | GAA (0.68) | GAANPC1ALDH1A1MAPTNPSR1 | |
| SCHEMBL9348273 | 0.74 | SLC6A4 (0.48) | ALDH1A1KDM4EMEN1KMT2ATP53 | |
| SCHEMBL2473900 | 0.73 | GAA (0.45) | GAANPC1ALDH1A1MAPTNPSR1 | |
| SCHEMBL3757554 | 0.73 | NPC1 (0.65) | GAANPC1ALDH1A1MAPTNPSR1 | |
| SCHEMBL7722871 | 0.72 | MAPK1 (0.42) | MAPK1 | |
| SCHEMBL5572861 | 0.72 | GAA (0.50) | GAANPC1ALDH1A1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009069132-A2 | NOVEL REVERSE TRANSCRIPTASE INHIBITORS | RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) | 2009-06-04 | — | — | WO | disclosed |