Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1427292 | 1.00 | LMNA (0.54) | LMNACYP2C9MEN1KMT2ATDP1 | |
| SCHEMBL29710926 | 1.00 | LMNA (0.54) | LMNACYP2C9MEN1KMT2ATDP1 | |
| SCHEMBL17972987 | 0.90 | — | — | |
| SCHEMBL13450308 | 0.81 | MEN1 (0.47) | LMNACYP2C9MEN1KMT2ATDP1 | |
| SCHEMBL16303393 | 0.79 | MEN1 (0.46) | LMNACYP2C9MEN1KMT2ATDP1 | |
| SCHEMBL8849930 | 0.79 | MEN1 (0.50) | LMNACYP2C9MEN1KMT2ATDP1 | |
| SCHEMBL7688345 | 0.79 | MEN1 (0.42) | LMNACYP2C9MEN1KMT2ATDP1 | |
| SCHEMBL17752558 | 0.76 | MEN1 (0.43) | LMNACYP2C9MEN1KMT2ATDP1 | |
| SCHEMBL6745315 | 0.75 | — | — | |
| SCHEMBL6081411 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009073942-A1 | TROPANE ALKALOIDS AND TRIGONELLINE COMBINATIONS AND METHODS FOR ADMINISTERING THE SAME | IOVATE T. & P. INC. (CA) | 2009-06-18 | — | — | WO | disclosed |
| US-20090156634-A1 | Tropane alkaloids and trigonelline combinations and methods for administering the same | IOVATE T. & P. INC. (CA) | 2009-06-18 | — | — | US | disclosed |