SCHEMBL4000386

SCHEMBL4000386

CCCCCCCCCCCCCCCCC(CC=CF)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GRIK1 P39086 2/20 0.51
▸ GRIK2 Q13002 2/20 0.51
▸ MAPT P10636 1/20 0.50
▸ SLC1A2 P43004 2/20 0.49
▸ SLC1A1 P43005 2/20 0.49
▸ CA2 P00918 2/20 0.48
▸ MAPK1 P28482 1/20 0.48
▸ GPR84 Q9NQS5 6/20 0.47
▸ FFAR1 O14842 2/20 0.47
▸ LCK P06239 1/20 0.46
▸ PPARD Q03181 1/20 0.46
▸ ZDHHC20 Q5W0Z9 1/20 0.46
▸ ZDHHC2 Q9UIJ5 1/20 0.46
▸ ACE2 Q9BYF1 1/20 0.43
▸ SLC1A3 P43003 1/20 0.42
▸ FFAR4 Q5NUL3 1/20 0.41
▸ CHRM1 P11229 1/20 0.41
▸ AKR1A1 P14550 1/20 0.41
▸ CHRM3 P20309 1/20 0.41
▸ HTR2A P28223 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7541186 0.84 GRIK1 (0.53) GRIK1GRIK2MAPTSLC1A2SLC1A1
SCHEMBL29076046 0.83 FFAR1 (0.59) GRIK1GRIK2MAPTFFAR1PPARD
SCHEMBL29255834 0.83 GRIK1 (0.51) GRIK1GRIK2MAPTSLC1A2SLC1A1
SCHEMBL11058489 0.83 GRIK1 (0.51) GRIK1GRIK2MAPTSLC1A2SLC1A1
SCHEMBL16927608 0.83 GRIK1 (0.51) GRIK1GRIK2MAPTSLC1A2SLC1A1
SCHEMBL31511854 0.83 FFAR1 (0.59) GRIK1GRIK2MAPTFFAR1PPARD
SCHEMBL16927603 0.83 FFAR1 (0.59) GRIK1GRIK2MAPTFFAR1PPARD
SCHEMBL1875643 0.82 CA2 (0.52) GRIK1GRIK2MAPTSLC1A2SLC1A1
SCHEMBL1875642 0.82 CA2 (0.52) GRIK1GRIK2MAPTSLC1A2SLC1A1
SCHEMBL23117047 0.80 GRIK1 (0.56) GRIK1GRIK2MAPTSLC1A2SLC1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1599184-A4 PERFLUOROCARBON AND HYDROFLUOROCARBON FORMULATIONS AND METHODS OF MAKING AND USING SAME CHRYSALIS TECH INC (US) 2009-06-24 — — EP claimed
EP-1599184-A1 PERFLUOROCARBON AND HYDROFLUOROCARBON FORMULATIONS AND METHODS OF MAKING AND USING SAME Chrysalis Technologies Incorporated (US) 2005-11-30 — — EP claimed
WO-2004071488-A1 PERFLUOROCARBON AND HYDROFLUOROCARBON FORMULATIONS AND METHODS OF MAKING AND USING SAME CHRYSALIS TECHNOLOGIES INCORPORATED (US) 2004-08-26 — — WO claimed
EP-1599184-A4 PERFLUOROCARBON AND HYDROFLUOROCARBON FORMULATIONS AND METHODS OF MAKING AND USING SAME CHRYSALIS TECH INC (US) 2009-06-24 — — EP disclosed
EP-1599184-A1 PERFLUOROCARBON AND HYDROFLUOROCARBON FORMULATIONS AND METHODS OF MAKING AND USING SAME Chrysalis Technologies Incorporated (US) 2005-11-30 — — EP disclosed
WO-2004071488-A1 PERFLUOROCARBON AND HYDROFLUOROCARBON FORMULATIONS AND METHODS OF MAKING AND USING SAME CHRYSALIS TECHNOLOGIES INCORPORATED (US) 2004-08-26 — — WO disclosed
US-5656347-A RELEASE COATING OF RESIN HAVING PERFLUORO SIDE CHAINS AND A FILM FORMING RESIN WHICH BINDS PERFLUORO RESIN TO A SUBSTRATE AMERICAN TAPE CO. (US) 1997-08-12 — — US disclosed
US-5451440-A Perfluoroalkyl acrylate polymers mixed with alkyd resin cured with amino resin AMERICAN TAPE CO. (US) 1995-09-19 — — US disclosed
WO-1995003937-A1 RELEASE COATING FOR SILICONE PRESSURE SENSITIVE ADHESIVES AMERICAN TAPE CO. (US) 1995-02-09 — — WO disclosed
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