Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 20/20 | 0.94 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.72 |
| ▸ | CNR1 | P21554 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4002500 | 0.99 | CNR2 (0.92) | CNR2KCNH2CNR1 | |
| SCHEMBL3998237 | 0.83 | CNR2 (1.00) | CNR2KCNH2CNR1 | |
| SCHEMBL17591208 | 0.83 | CNR2 (0.75) | CNR2CNR1 | |
| SCHEMBL3997928 | 0.83 | CNR2 (0.75) | CNR2CNR1 | |
| Hydrochloric Acid SCHEMBL3995359 | 0.82 | CNR2 (0.98) | CNR2KCNH2CNR1 | |
| SCHEMBL14074475 | 0.81 | CNR2 (0.64) | CNR2KCNH2CNR1 | |
| SCHEMBL4966183 | 0.81 | CNR2 (0.64) | CNR2KCNH2CNR1 | |
| SCHEMBL5120916 | 0.81 | CNR2 (0.63) | CNR2KCNH2CNR1 | |
| SCHEMBL5126974 | 0.80 | CNR2 (0.62) | CNR2KCNH2CNR1 | |
| SCHEMBL4968503 | 0.80 | CNR2 (0.62) | CNR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7598393-B2 | Sulfonyl benzimidazole derivatives | PFIZER INC. (US) | 2009-10-06 | — | — | US | claimed |
| EP-1809607-B1 | SULFONYL BENZIMIDAZOLE DERIVATIVES | PFIZER (US) | 2008-12-17 | — | — | EP | claimed |
| US-20060094750-A1 | Sulfonyl benzimidazole derivatives | KON-I KANA | 2006-05-04 | — | — | US | claimed |
| US-7598393-B2 | Sulfonyl benzimidazole derivatives | PFIZER INC. (US) | 2009-10-06 | — | — | US | disclosed |
| EP-1809607-B1 | SULFONYL BENZIMIDAZOLE DERIVATIVES | PFIZER (US) | 2008-12-17 | — | — | EP | disclosed |
| US-20060094750-A1 | Sulfonyl benzimidazole derivatives | KON-I KANA | 2006-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094750-A1 | Sulfonyl benzimidazole derivatives | TRPV1, CNR2, CNR1 | CNR2 2/4885KCNH2 331/4885CNR1 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.