Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 19/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5010605 | 0.94 | CNR2 (0.54) | CNR2KCNH2PTGER4 | |
| SCHEMBL4968426 | 0.85 | CNR2 (0.65) | CNR2KCNH2 | |
| SCHEMBL4000595 | 0.80 | CNR2 (0.94) | CNR2KCNH2 | |
| Hydrochloric Acid SCHEMBL4002500 | 0.79 | CNR2 (0.92) | CNR2KCNH2 | |
| SCHEMBL5120916 | 0.79 | CNR2 (0.63) | CNR2KCNH2 | |
| SCHEMBL4969898 | 0.79 | CNR2 (0.56) | CNR2 | |
| SCHEMBL14074475 | 0.78 | CNR2 (0.64) | CNR2KCNH2 | |
| SCHEMBL4966183 | 0.78 | CNR2 (0.64) | CNR2KCNH2 | |
| SCHEMBL4970666 | 0.76 | CNR2 (0.54) | CNR2 | |
| SCHEMBL5126974 | 0.76 | CNR2 (0.62) | CNR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1670770-B1 | BENZIMIDAZOLE DERIVATIVES, COMPOSITIONS CONTAINING THEM, PREPARATION THEROF AND USES THEREOF | ASTRAZENECA AB (SE) | 2008-08-20 | — | — | EP | disclosed |