SCHEMBL4001003

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4001200	0.90	MAOB (0.54)	ADORA2AMAOBADORA3ADORA1GSK3B
	SCHEMBL4005923	0.89	MAOB (0.49)	ADORA2AMAOBADORA3ADORA1GSK3B
	SCHEMBL4004828	0.84	GSK3B (0.47)	ADORA2AMAOBADORA3ADORA1GSK3B
	SCHEMBL4001941	0.82	GSK3B (0.47)	ADORA2AMAOBADORA3ADORA1GSK3B
	SCHEMBL4008764	0.81	GSK3B (0.43)	ADORA2AMAOBADORA3ADORA1GSK3B
	SCHEMBL4000917	0.79	GSK3B (0.42)	ADORA2AMAOBADORA3ADORA1GSK3B
	SCHEMBL4316108	0.77	GSK3B (0.46)	GSK3BCYP2D6CYP1A2
	SCHEMBL4006674	0.77	ADORA2A (0.43)	ADORA2AGSK3BCYP2D6CYP1A2
	SCHEMBL4007227	0.77	GSK3B (0.42)	MAOBGSK3BCYP2D6MEN1KMT2A
	SCHEMBL4005931	0.77	MAOB (0.50)	MAOBGSK3BKDM4EALDH1A1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.