Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 18/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6849201 | 1.00 | CYP19A1 (0.40) | CYP19A1ARESR1 | |
| SCHEMBL6853911 | 1.00 | CYP19A1 (0.40) | CYP19A1ARESR1 | |
| SCHEMBL13809850 | 1.00 | CYP19A1 (0.40) | CYP19A1ARESR1 | |
| SCHEMBL13804521 | 1.00 | CYP19A1 (0.40) | CYP19A1ARESR1 | |
| SCHEMBL3999426 | 1.00 | CYP19A1 (0.40) | CYP19A1ARESR1 | |
| SCHEMBL6854222 | 0.90 | CYP19A1 (0.40) | CYP19A1ARESR1 | |
| SCHEMBL6852290 | 0.90 | CYP19A1 (0.40) | CYP19A1ARESR1 | |
| SCHEMBL6852404 | 0.89 | CYP19A1 (0.40) | CYP19A1ARESR1 | |
| SCHEMBL6853763 | 0.89 | CYP19A1 (0.40) | CYP19A1ARESR1 | |
| SCHEMBL6912936 | 0.86 | CYP19A1 (0.37) | CYP19A1ARESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2070941-A1 | Stereoselective synthesis of selective estrogen receptor down-regulators | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-06-17 | — | — | EP | disclosed |