Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.61 |
| ▸ | ESR1 | P03372 | 13/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 13/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3193340 | 0.82 | APP (0.83) | APPESR1ESR2NPC1RAB9A | |
| SCHEMBL13419394 | 0.78 | APP (0.93) | APPESR1ESR2NPC1RAB9A | |
| SCHEMBL16901788 | 0.73 | ESR1 (0.68) | APPESR1ESR2NPC1RAB9A | |
| SCHEMBL9197515 | 0.73 | ESR1 (0.68) | ESR1ESR2NPC1RAB9A | |
| SCHEMBL3181272 | 0.72 | APP (0.84) | APPESR1ESR2NPC1RAB9A | |
| SCHEMBL8034090 | 0.72 | ESR1 (0.81) | APPESR1ESR2NPC1RAB9A | |
| SCHEMBL27090228 | 0.70 | ESR1 (0.96) | APPESR1ESR2NPC1RAB9A | |
| SCHEMBL17561646 | 0.70 | ESR1 (0.81) | ESR1ESR2NPC1RAB9A | |
| SCHEMBL27090259 | 0.69 | ESR1 (0.75) | APPESR1ESR2NPC1RAB9A | |
| SCHEMBL13419359 | 0.69 | APP (0.93) | APPESR1ESR2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035418-A1 | NOVEL HETEROARYL SUBSTITUTED BENZOXAZOLES | Astra Zeneca AB (SE) | 2009-03-18 | — | — | EP | claimed |
| WO-2007149030-A1 | NOVEL HETEROARYL SUBSTITUTED BENZOXAZOLES | ASTRAZENECA AB (SE) | 2007-12-27 | — | — | WO | claimed |