Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 11/20 | 0.78 |
| ▸ | ACACA | Q13085 | 7/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | TACR3 | P29371 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4008494 | 0.94 | ACACB (0.80) | ACACBACACACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4007641 | 0.89 | ACACB (0.74) | ACACBACACACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4391971 | 0.89 | ACACB (0.74) | ACACBACACACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4391974 | 0.89 | ACACB (0.74) | ACACBACACACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL13590592 | 0.88 | ACACB (1.00) | ACACBACACACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4002276 | 0.88 | ACACB (0.73) | ACACBACACACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4393382 | 0.87 | ACACB (0.71) | ACACBACACACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4393385 | 0.87 | ACACB (0.71) | ACACBACACACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4007635 | 0.87 | ACACB (0.71) | ACACBACACACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4005864 | 0.86 | ACACB (0.79) | ACACBACACACYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009082346-A1 | NEW ACETYL COENZYME A CARBOXYLASE (ACC) INHIBITORS AND USES IN TREATMENTS OF OBESITY AND DIABETES MELLITUS - 087 | ASTRAZENECA AB (SE) | 2009-07-02 | — | — | WO | disclosed |