Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 9/20 | 0.74 |
| ▸ | ACACA | Q13085 | 6/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | TACR3 | P29371 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4391971 | 0.91 | ACACB (0.74) | ACACBACACAALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL4391974 | 0.91 | ACACB (0.74) | ACACBACACAALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL4002278 | 0.89 | ACACB (0.78) | ACACBACACAALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL4007635 | 0.89 | ACACB (0.71) | ACACBACACAALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL4393382 | 0.89 | ACACB (0.71) | ACACBACACAALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL4393385 | 0.89 | ACACB (0.71) | ACACBACACAALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL4008278 | 0.88 | ACACB (0.60) | ACACBACACAALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL4009702 | 0.87 | ACACB (0.69) | ACACBACACAALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL4390184 | 0.87 | ACACB (0.69) | ACACBACACAALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL13590677 | 0.86 | ACACB (0.77) | ACACBACACAALDH1A1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009082346-A1 | NEW ACETYL COENZYME A CARBOXYLASE (ACC) INHIBITORS AND USES IN TREATMENTS OF OBESITY AND DIABETES MELLITUS - 087 | ASTRAZENECA AB (SE) | 2009-07-02 | — | — | WO | disclosed |