Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 11/20 | 1.00 |
| ▸ | CPA1 | P15085 | 2/20 | 0.53 |
| ▸ | GABRP | O00591 | 2/20 | 0.51 |
| ▸ | GABRD | O14764 | 2/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.51 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.51 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.51 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.51 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.51 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.51 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.51 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.51 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.51 |
| ▸ | GABRE | P78334 | 2/20 | 0.51 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.51 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.51 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.51 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.51 |
| ▸ | CPB1 | P15086 | 9/20 | 0.50 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4005719 | 1.00 | CPB2 (1.00) | CPB2CPA1GABRPGABRDGABRA1 | |
| SCHEMBL4012774 | 1.00 | CPB2 (1.00) | CPB2CPA1GABRPGABRDGABRA1 | |
| SCHEMBL5075309 | 0.87 | CPB2 (0.76) | CPB2CPA1GABRPGABRDGABRA1 | |
| SCHEMBL4009716 | 0.86 | CPB2 (0.75) | CPB2CPA1GABRPGABRDGABRA1 | |
| SCHEMBL18057309 | 0.81 | CPB2 (0.68) | CPB2CPA1GABRPGABRDGABRA1 | |
| SCHEMBL4509644 | 0.79 | CPB2 (0.65) | CPB2CPA1GABRPGABRDGABRA1 | |
| SCHEMBL5079022 | 0.79 | CPB2 (0.65) | CPB2CPA1GABRPGABRDGABRA1 | |
| SCHEMBL4009042 | 0.79 | CPB2 (0.64) | CPB2CPA1GABRPGABRDGABRA1 | |
| SCHEMBL4507391 | 0.78 | CPB2 (0.63) | CPB2CPA1GABRPGABRDGABRA1 | |
| SCHEMBL4510175 | 0.78 | CPB2 (0.62) | CPB2CPA1GABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009082340-A1 | METHOD FOR MONITORING THE PROGRESSION OF FIBRINOLYSIS'646 | ASTRAZENECA AB (SE) | 2009-07-02 | — | — | WO | disclosed |
| US-7071175-B1 | Pyridine mercapto carboxylic acids as carboxypeptidase U inhibitors | ASTRAZENECA AB (SE) | 2006-07-04 | — | — | US | disclosed |
| EP-1180098-A1 | NEW COMPOUNDS | AstraZeneca AB (SE) | 2002-02-20 | — | — | EP | disclosed |
| WO-2000066557-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 2000-11-09 | — | — | WO | disclosed |