Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4007591 | 1.00 | ALDH1A1 (0.32) | ALDH1A1LMNAHSD17B10TSHR | |
| Hydrochloric Acid SCHEMBL4002384 | 0.98 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL2223785 | 0.79 | — | — | |
| SCHEMBL6294622 | 0.79 | — | — | |
| SCHEMBL14584578 | 0.77 | ALDH1A1 (0.33) | ALDH1A1LMNAHSD17B10 | |
| Hydrochloric Acid SCHEMBL6294621 | 0.77 | — | — | |
| SCHEMBL7100271 | 0.76 | — | — | |
| SCHEMBL9024028 | 0.76 | ALDH1A1 (0.36) | ALDH1A1LMNAHSD17B10 | |
| Hydrochloric Acid SCHEMBL4428151 | 0.74 | — | — | |
| SCHEMBL442749 | 0.72 | ALDH1A1 (0.46) | ALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009074677-A2 | PYRAZOLOTRIAZINES | 4SC AG (DE) | 2009-06-18 | — | — | WO | disclosed |
| EP-2070932-A1 | Pyrazolotriazines | 4SC AG (DE) | 2009-06-17 | — | — | EP | disclosed |