Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 19/20 | 0.82 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1365787 | 0.89 | MCHR1 (0.71) | MCHR1MAPK14KCNH2 | |
| SCHEMBL1365313 | 0.84 | MCHR1 (0.73) | MCHR1MAPK14KCNH2 | |
| SCHEMBL1364736 | 0.82 | MCHR1 (0.73) | MCHR1MAPK14KCNH2 | |
| SCHEMBL1364955 | 0.81 | MCHR1 (0.72) | MCHR1MAPK14KCNH2 | |
| SCHEMBL15249806 | 0.80 | MCHR1 (1.00) | MCHR1 | |
| SCHEMBL4045683 | 0.79 | MAPK14 (0.74) | MCHR1MAPK14KCNH2 | |
| SCHEMBL1364816 | 0.77 | MCHR1 (0.82) | MCHR1MAPK14KCNH2 | |
| SCHEMBL12162794 | 0.77 | MCHR1 (0.66) | MCHR1MAPK14KCNH2 | |
| SCHEMBL2881955 | 0.77 | MCHR1 (1.00) | MCHR1KCNH2 | |
| SCHEMBL2881740 | 0.77 | MCHR1 (0.81) | MCHR1MAPK14KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069327-A1 | NEW PYRIDONE DERIVATIVES WITH MCH ANTAGONISTIC ACTIVITY AND MEDICAMENTS COMPRISING THESE COMPOUNDS | Boehringer Ingelheim International GmbH (DE) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008022979-A1 | NEW PYRIDONE DERIVATIVES WITH MCH ANTAGONISTIC ACTIVITY AND MEDICAMENTS COMPRISING THESE COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-02-28 | — | — | WO | disclosed |