Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 8/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4003447 | 1.00 | HSD11B1 (0.66) | HSD11B1L3MBTL1EPHX2RAB9ACNR2 | |
| SCHEMBL4005124 | 0.89 | HSD11B1 (0.64) | HSD11B1L3MBTL1RAB9ACNR2 | |
| SCHEMBL4005127 | 0.89 | HSD11B1 (0.64) | HSD11B1L3MBTL1RAB9ACNR2 | |
| SCHEMBL4006076 | 0.88 | HSD11B1 (0.63) | HSD11B1L3MBTL1CNR2 | |
| SCHEMBL4006086 | 0.88 | HSD11B1 (0.63) | HSD11B1L3MBTL1CNR2 | |
| SCHEMBL4010554 | 0.87 | HSD11B1 (0.75) | HSD11B1EPHX2RAB9AALDH1A1 | |
| SCHEMBL612467 | 0.87 | HSD11B1 (0.75) | HSD11B1EPHX2RAB9AALDH1A1 | |
| SCHEMBL4006859 | 0.86 | HSD11B1 (0.61) | HSD11B1L3MBTL1EPHX2RAB9ACNR2 | |
| SCHEMBL4006852 | 0.86 | HSD11B1 (0.61) | HSD11B1L3MBTL1EPHX2RAB9ACNR2 | |
| SCHEMBL4009206 | 0.86 | HSD11B1 (0.68) | HSD11B1L3MBTL1CNR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778229-A4 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2009-06-17 | — | — | EP | disclosed |
| EP-1778229-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006020598-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-02-23 | — | — | WO | disclosed |