Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | CCR3 | P51677 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | TARDBP | Q13148 | 1/20 | 0.38 |
| ▸ | GALR3 | O60755 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL400551 | 1.00 | ADRB2 (0.41) | ADRB2RAB9AKDM4EKMT2AMEN1 | |
| SCHEMBL400753 | 1.00 | ADRB2 (0.41) | ADRB2RAB9AKDM4EKMT2AMEN1 | |
| SCHEMBL403108 | 0.95 | CCR3 (0.41) | RAB9ANPC1MAPTPKMSMN1; SMN2 | |
| SCHEMBL403110 | 0.95 | CCR3 (0.41) | RAB9ANPC1MAPTPKMSMN1; SMN2 | |
| SCHEMBL4006418 | 0.95 | CCR3 (0.41) | RAB9ANPC1MAPTPKMSMN1; SMN2 | |
| SCHEMBL545088 | 0.92 | ADRB2 (0.44) | ADRB2RAB9AKDM4EKMT2AMEN1 | |
| SCHEMBL4012615 | 0.92 | ADRB2 (0.44) | ADRB2RAB9AKDM4EKMT2AMEN1 | |
| SCHEMBL545169 | 0.92 | ADRB2 (0.44) | ADRB2RAB9AKDM4EKMT2AMEN1 | |
| SCHEMBL398834 | 0.90 | KCNH2 (0.43) | RAB9AKDM4ENPC1MAPTPKM | |
| SCHEMBL4012403 | 0.90 | KMT2A (0.41) | ADRB2RAB9AKDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765327-A4 | COMPOUNDS, COMPOSITIONS AND METHODS | CYTOKINETICS INC (US) | 2009-06-17 | — | — | EP | claimed |
| EP-1765327-A2 | COMPOUNDS, COMPOSITIONS AND METHODS | Cytokinetics, Inc. (US) | 2007-03-28 | — | — | EP | claimed |
| WO-2006009726-A2 | SUBSTITUTED UREA DERIVATIVES FOR TREATING CARDIAC DISEASES | CYTOKINETICS, INC. (US) | 2006-01-26 | — | — | WO | claimed |
| EP-1765327-A4 | COMPOUNDS, COMPOSITIONS AND METHODS | CYTOKINETICS INC (US) | 2009-06-17 | — | — | EP | disclosed |
| EP-1765327-A2 | COMPOUNDS, COMPOSITIONS AND METHODS | Cytokinetics, Inc. (US) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006009726-A2 | SUBSTITUTED UREA DERIVATIVES FOR TREATING CARDIAC DISEASES | CYTOKINETICS, INC. (US) | 2006-01-26 | — | — | WO | disclosed |