Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3995895 | 0.77 | HDAC8 (0.31) | CYP3A4TSHRHDAC8 | |
| SCHEMBL4002816 | 0.77 | HAO1 (0.45) | ALDH1A1SMN1; SMN2POLBTDP1NPSR1 | |
| SCHEMBL4003856 | 0.72 | KMT2A (0.40) | ALDH1A1SMN1; SMN2POLBTSHRTDP1 | |
| SCHEMBL5566257 | 0.69 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2CYP3A4TSHRKDM4E | |
| SCHEMBL25370601 | 0.69 | HDAC8 (0.31) | HDAC8GAA | |
| SCHEMBL458268 | 0.68 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2POLBCYP2C9CYP3A4 | |
| SCHEMBL4001321 | 0.68 | HSP90AA1 (0.36) | SMN1; SMN2CYP2C9CYP3A4TSHRNPSR1 | |
| SCHEMBL2751328 | 0.68 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2POLBCYP2C9CYP3A4 | |
| SCHEMBL13317292 | 0.66 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2POLBCYP2C9CYP3A4 | |
| Phosphine SCHEMBL22361930 | 0.66 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2POLBCYP2C9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066643-A1 | PYRIDAZIN-4-YLMETHYL-SULFONAMIDES USED AS FUNGICIDES AND AGAINST ARTHROPODS | BASF SE (DE) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008062012-A1 | PYRIDAZIN-4-YLMETHYL-SULFONAMIDES USED AS FUNGICIDES AND AGAINST ARTHROPODS | BASF SE (DE) | 2008-05-29 | — | — | WO | disclosed |