SCHEMBL4004717

SCHEMBL4004717

CCO[Si](CN(CCCN(C)C)CCCN(C)C)(OCC)OCC

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.35
TSHR P16473 1/20 0.35
DNM1 Q05193 3/20 0.34
KDM4E B2RXH2 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16813999 0.85 SLC2A1 (0.36)
SCHEMBL16813579 0.84 KDM5A (0.31)
SCHEMBL16813540 0.83
SCHEMBL916052 0.83 CA12 (0.31)
SCHEMBL16813486 0.82 KDM5A (0.33)
SCHEMBL16813970 0.82 DNM1 (0.33) ALDH1A1TSHRDNM1KDM4ESMN1; SMN2
SCHEMBL16814012 0.82 DNM1 (0.33) ALDH1A1TSHRDNM1KDM4ESMN1; SMN2
SCHEMBL16225035 0.82 DNM1 (0.33) ALDH1A1TSHRDNM1KDM4ESMN1; SMN2
SCHEMBL16813095 0.82 DNM1 (0.33) ALDH1A1TSHRDNM1KDM4ESMN1; SMN2
SCHEMBL16813960 0.80 SLC2A1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9062182-B2 Terminal modifier for conjugated diene polymers KOREA KUMBO PETROCHEMICAL CO., LTD. (KR) 2015-06-23 US claimed
US-9062182-B2 Terminal modifier for conjugated diene polymers KOREA KUMBO PETROCHEMICAL CO., LTD. (KR) 2015-06-23 US disclosed
EP-1879956-B1 METHOD FOR PRODUCING CROSSLINKABLE ORGANOPOLYSILOXANE DISPERSIONS WACKER CHEMIE AG (DE) 2013-03-06 EP disclosed
US-8304023-B2 coating with a condensation-curable organopolysiloxanes with silanes to form elastomeric films insoluble in toluene; formed layer has a permanent soft hand and good bulk, no yellowing, free of volatile organic compounds; storage stability, solvent-free WACKER CHEMIE AG (DE) 2012-11-06 US disclosed
EP-1721926-B1 Process for the production of dispersions of cross linked organopolysiloxanes WACKER CHEMIE AG (DE) 2009-07-01 EP disclosed
EP-1921203-B1 Treatment of fiberfill fibers with aqueous dispersions of organopolysiloxanes WACKER CHEMIE AG (DE) 2009-06-17 EP disclosed
EP-1921106-A1 Preparation of aqueous dispersions of organopolysiloxanes Wacker Chemie AG (DE) 2008-05-14 EP disclosed
EP-1921203-A1 Treatment of fiberfill fibers with aqueous dispersions of organopolysiloxanes Wacker Chemie AG (DE) 2008-05-14 EP disclosed
US-20080107815-A1 Preparation Of Aqueous Dispersions Of Organopolysiloxanes WACKER CHEMIE AG (DE) 2008-05-08 US disclosed
US-20080107814-A1 Treatment Of Fiberfill Fibers With Aqueous Dispersions Of Organopolysiloxanes WACKER CHEMIE AG (DE) 2008-05-08 US disclosed
US-20080064813-A1 METHOD FOR PRODUCING CROSSLINKABLE ORGANOPOLYSILOXANE DISPERSIONS WACKER CHEMIE AG (DE) 2008-03-13 US disclosed
US-20060258820-A1 Process for preparing dispersions of crosslinked organopolysiloxanes WACKER CHEMIE AG (DE) 2006-11-16 US disclosed
EP-1721926-A1 Process for the production of dispersions of cross linked organopolysiloxanes Wacker Chemie AG (DE) 2006-11-15 EP disclosed