Thiophosphoric Acid Dodecyl Ester

Thiophosphoric Acid Dodecyl Ester

SCHEMBL40052

CCCCCCCCCCCCOP(O)(O)=S

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 19/20 1.00
LPAR2 Q9HBW0 15/20 1.00
LPAR1 Q92633 13/20 0.78
LPAR6 P43657 4/20 0.59
LPAR4 Q99677 4/20 0.59
LPAR5 Q9H1C0 4/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1974389 1.00 LPAR3 (1.00) LPAR3LPAR2LPAR1LPAR6LPAR4
SCHEMBL258195 1.00 LPAR3 (1.00) LPAR3LPAR2LPAR1LPAR6LPAR4
SCHEMBL40320 1.00 LPAR3 (1.00) LPAR3LPAR2LPAR1LPAR6LPAR4
Thiophosphoric Acid Decyl Ester SCHEMBL194340 1.00 LPAR3 (1.00) LPAR3LPAR2LPAR1LPAR6LPAR4
Thiophosphoric Acid Tetradecyl Ester SCHEMBL193777 1.00 LPAR3 (1.00) LPAR3LPAR2LPAR1LPAR6LPAR4
SCHEMBL8657418 1.00 LPAR3 (1.00) LPAR3LPAR2LPAR1LPAR6LPAR4
SCHEMBL8469365 1.00 LPAR3 (1.00) LPAR3LPAR2LPAR1LPAR6LPAR4
SCHEMBL8372319 1.00 LPAR3 (1.00) LPAR3LPAR2LPAR1LPAR6LPAR4
SCHEMBL6695704 1.00 LPAR3 (1.00) LPAR3LPAR2LPAR1LPAR6LPAR4
SCHEMBL31749062 1.00 LPAR3 (1.00) LPAR3LPAR2LPAR1LPAR6LPAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2481743-B1 LPA receptor agonists and antagonists and methods of use UNIV TENNESSEE RES FOUND (US) 2017-03-22 EP claimed
EP-2433946-B1 LPA receptor agonists and antagonists and methods of use UNIV TENNESSEE RES FOUNDATION (US) 2016-04-20 EP claimed
CN-102766505-B Ashless anti-wear oil film bearing lubricating oil composition CHINA NAT PETROLEUM CORP 2014-08-06 CN claimed
CN-102766505-A Ashless anti-wear oil film bearing lubricating oil composition CHINA NAT PETROLEUM CORP 2012-11-07 CN claimed
EP-2481743-A1 LPA receptor agonists and antagonists and methods of use UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2012-08-01 EP claimed
EP-2433946-A1 LPA receptor agonists and antagonists and methods of use University of Tennessee Research Foundation (US) 2012-03-28 EP claimed
EP-1906972-A2 LPA2 RECEPTOR AGONIST INHIBITORS OF CFTR The University of Tennessee Research Foundation (US) 2008-04-09 EP claimed
US-20070078111-A1 LPA2 receptor agonist inhibitors of CFTR NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2007-04-05 US claimed
WO-2007011905-A2 LPA2 RECEPTOR AGONIST INHIBITORS OF CFTR THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2007-01-25 WO claimed
US-20060009507-A1 Thio-phosphoric and -phosphorous acid derivatives; treating cancer, wounds, skin disorders and apoptosis; preserving or restoring function in a cell, tissue or organ; culturing cells; preserving organ or tissue function; and enhancing cell proliferation UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2006-01-12 US claimed
EP-4562707-A1 BATTERY THERMAL MANAGEMENT AND SAFETY METHOD AND DEVICE FOR IMPLEMENTING SAME TotalEnergies OneTech (FR) 2025-06-04 EP disclosed
EP-4551676-A1 USE OF AN ANTI-WEAR ADDITIVE FOR IMPROVING THE THERMAL CONDUCTIVITY OF A COOLING FLUID FOR AN ELECTRIC VEHICLE TotalEnergies OneTech (FR) 2025-05-14 EP disclosed
CN-119421940-A Use of antiwear additives for increasing the thermal conductivity of cooling fluids for electric vehicles 总和营销服务 2025-02-11 CN disclosed
US-20240336866-A1 AQUEOUS LUBRICANT COMPOSITION FOR METALWORKING TOTALENERGIES ONETECH (FR) 2024-10-10 US disclosed
EP-4363537-A1 AQUEOUS LUBRICANT COMPOSITION FOR METALWORKING TotalEnergies OneTech (FR) 2024-05-08 EP disclosed
US-5241003-A Post-treated polyisobutenyl succinimide; crankcase, transmission oils ETHYL PETROLEUM ADDITIVES, INC. (US) 1993-08-31 US disclosed
EP-0531585-A1 Oil additive concentrates and lubricants of enhanced performance capabilities ETHYL PETROLEUM ADDITIVES LIMITED (GB) 1993-03-17 EP disclosed
US-5137980-A Reacting polyisobutene with aacidic reactant; super atmospheric pressure; low tar rating ETHYL PETROLEUM ADDITIVES, INC. (US) 1992-08-11 US disclosed
EP-0460317-A1 Polyalkylene glycol lubricant compositions ETHYL PETROLEUM ADDITIVES LIMITED (GB) 1991-12-11 EP disclosed
EP-0459656-A1 Lubricant compositions ETHYL PETROLEUM ADDITIVES, INC. (US) 1991-12-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060009507-A1 Thio-phosphoric and -phosphorous acid derivatives; treating cancer, wounds, skin disorders and apoptosis; preserving or restoring function in a cell, tissue or organ; culturing cells; preserving organ or tissue function; and enhancing cell proliferation LPAR1, LPAR6, LPAR2 LPAR3 6/4885LPAR2 3/4885LPAR1 1/4885
US-20070078111-A1 LPA2 receptor agonist inhibitors of CFTR LPAR2, NHERF1, LPAR1 LPAR3 6/4885LPAR2 1/4885LPAR1 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.