Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 9/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | GLS2 | Q9UI32 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MPEG1 | Q2M385 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL437556 | 0.98 | ACHE (0.47) | ACHEBACE1ALOX5PTGS2PTPN1 | |
| SCHEMBL1578870 | 0.96 | ACHE (0.50) | ACHEBACE1ALOX5PTGS2PTPN1 | |
| SCHEMBL65638 | 0.96 | ACHE (0.50) | ACHEBACE1ALOX5PTGS2PTPN1 | |
| SCHEMBL1578823 | 0.96 | ACHE (0.50) | ACHEBACE1ALOX5PTGS2PTPN1 | |
| SCHEMBL465095 | 0.96 | ACHE (0.50) | ACHEBACE1ALOX5PTGS2PTPN1 | |
| SCHEMBL36399 | 0.96 | ACHE (0.50) | ACHEBACE1ALOX5PTGS2PTPN1 | |
| SCHEMBL1578876 | 0.96 | ACHE (0.50) | ACHEBACE1ALOX5PTGS2PTPN1 | |
| SCHEMBL14720387 | 0.96 | ACHE (0.50) | ACHEBACE1ALOX5PTGS2PTPN1 | |
| SCHEMBL12501883 | 0.96 | ACHE (0.50) | ACHEBACE1ALOX5PTGS2PTPN1 | |
| SCHEMBL1578445 | 0.96 | ACHE (0.50) | ACHEBACE1ALOX5PTGS2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1708995-B1 | ASPARTATES USEFUL AS COMPONENTS IN COATING COMPOSITIONS AND THEIR PREPARATION | BAYER MATERIALSCIENCE LLC (US) | 2013-02-27 | — | — | EP | disclosed |
| EP-1666461-B1 | Polyaspartimides useful as reactive components for polyisocyanates in two-component polyurethane coating compositions | BAYER MATERIALSCIENCE AG (DE) | 2009-06-24 | — | — | EP | disclosed |
| EP-1708995-A1 | ASPARTATES USEFUL AS COMPONENTS IN COATING COMPOSITIONS AND THEIR PREPARATION | Bayer MaterialScience LLC (US) | 2006-10-11 | — | — | EP | disclosed |
| EP-1666461-A2 | Polyaspartimides useful as reactive components for polyisocyanates in two-component polyurethane coating compositions | Bayer MaterialScience AG (DE) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005073188-A1 | ASPARTATES USEFUL AS COMPONENTS IN COATING COMPOSITIONS AND THEIR PREPARATION | BAYER MATERIALSCIENCE LLC (US) | 2005-08-11 | — | — | WO | disclosed |