Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 4/20 | 0.49 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.44 |
| ▸ | CPA3 | P15088 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 2/20 | 0.40 |
| ▸ | GABRP | O00591 | 2/20 | 0.39 |
| ▸ | GABRD | O14764 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.39 |
| ▸ | GABRE | P78334 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4013410 | 0.83 | CPB2 (0.49) | CPB2MMEGABRPGABRDGABRA1 | |
| Hydrochloric Acid SCHEMBL7384117 | 0.82 | CPB2 (0.48) | CPB2MMEGABRPGABRDGABRA1 | |
| SCHEMBL6060165 | 0.81 | CPB2 (0.47) | CPB2MMEGABRPGABRDGABRA1 | |
| SCHEMBL4010482 | 0.80 | CPB2 (0.46) | CPB2P4HTMMMEGABRPGABRD | |
| SCHEMBL4007311 | 0.77 | CPB2 (0.55) | CPB2MMEGABRPGABRDGABRA1 | |
| SCHEMBL4007432 | 0.75 | CPB2 (0.52) | CPB2MMEGABRPGABRDGABRA1 | |
| SCHEMBL27463356 | 0.71 | SLC6A2 (0.53) | CPB2P4HTMGABRPGABRDGABRA1 | |
| SCHEMBL27517825 | 0.71 | CPB2 (0.42) | CPB2P4HTMGABRPGABRDGABRA1 | |
| SCHEMBL27544388 | 0.69 | CPB2 (0.48) | CPB2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL5073961 | 0.68 | CPB2 (0.61) | CPB2SLC1A3SLC1A2SLC1A1GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009082340-A1 | METHOD FOR MONITORING THE PROGRESSION OF FIBRINOLYSIS'646 | ASTRAZENECA AB (SE) | 2009-07-02 | — | — | WO | disclosed |
| US-7071175-B1 | Pyridine mercapto carboxylic acids as carboxypeptidase U inhibitors | ASTRAZENECA AB (SE) | 2006-07-04 | — | — | US | disclosed |
| EP-1180098-A1 | NEW COMPOUNDS | AstraZeneca AB (SE) | 2002-02-20 | — | — | EP | disclosed |
| WO-2000066557-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 2000-11-09 | — | — | WO | disclosed |