Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 5/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 5/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | HTR2B | P41595 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL15558160 | 1.00 | HTR2C (0.34) | HTR2CCHRNA7DPP4DPP8DPP7 | |
| Trifluoroacetic Acid SCHEMBL4836781 | 1.00 | HTR2C (0.34) | HTR2CCHRNA7DPP4DPP8DPP7 | |
| Trifluoroacetic Acid SCHEMBL2916218 | 1.00 | HTR2C (0.34) | HTR2CCHRNA7DPP4DPP8DPP7 | |
| Trifluoroacetic Acid SCHEMBL29996327 | 0.80 | HTR2C (0.36) | HTR2CCHRNA7DPP4DPP8DPP7 | |
| Trifluoroacetic Acid SCHEMBL21847051 | 0.79 | HTR2C (0.35) | HTR2CCHRNA7DPP4DPP8DPP7 | |
| Trifluoroacetic Acid SCHEMBL15547392 | 0.79 | HTR2C (0.35) | HTR2CCHRNA7DPP4DPP8DPP7 | |
| Trifluoroacetic Acid SCHEMBL25267493 | 0.78 | IRAK4 (0.37) | CHRNA7DPP4DPP8DPP7SLC6A3 | |
| Trifluoroacetic Acid SCHEMBL21816594 | 0.78 | PKM (0.36) | HTR2CDPP4DPP8DPP7HTR2A | |
| Trifluoroacetic Acid SCHEMBL21816711 | 0.78 | PKM (0.36) | HTR2CDPP4DPP8DPP7HTR2A | |
| Trifluoroacetic Acid SCHEMBL2917931 | 0.78 | PKM (0.36) | HTR2CDPP4DPP8DPP7HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7521441-B2 | Cyclopropyl fused indolobenzazepine HCV NS5B inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-04-21 | — | — | US | disclosed |
| US-7517872-B2 | Compounds for the treatment of hepatitis C | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-04-14 | — | — | US | disclosed |
| US-20080206191-A1 | Compounds for the Treatment of Hepatitis C | BRISTOL-MYERS SQUIBB COMPANY | 2008-08-28 | — | — | US | disclosed |
| WO-2007140109-A1 | CYCLOPROPYL FUSED INDOLOBENZAZEPINE HCV NS5B INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-12-06 | — | — | WO | disclosed |
| US-20070270406-A1 | Cyclopropyl Fused Indolobenzazepine HCV NS5B Inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2007-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070270406-A1 | Cyclopropyl Fused Indolobenzazepine HCV NS5B Inhibitors | HAVCR2, ZC3HAV1, HCCS | HTR2C 725/4885CHRNA7 3779/4885DPP4 297/4885 |
| US-20080206191-A1 | Compounds for the Treatment of Hepatitis C | HAVCR2, HCCS, SLC10A1 | HTR2C 3167/4885CHRNA7 4647/4885DPP4 806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.