Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.47 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 10/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4004728 | 0.88 | SLC6A9 (0.49) | SLC6A9SSTR4SCN9AOPRM1OPRL1 | |
| SCHEMBL4006087 | 0.83 | SSTR4 (0.54) | SLC6A9SSTR4SCN9AOPRM1OPRL1 | |
| SCHEMBL4007365 | 0.83 | SSTR4 (0.54) | SLC6A9SSTR4SCN9AOPRM1OPRL1 | |
| SCHEMBL4005570 | 0.81 | SSTR4 (0.49) | SLC6A9SSTR4SCN9AOPRM1OPRL1 | |
| SCHEMBL4007336 | 0.80 | SSTR4 (0.48) | SLC6A9SSTR4SCN9AOPRM1OPRL1 | |
| SCHEMBL4552161 | 0.78 | SSTR4 (0.49) | SLC6A9SSTR4SCN9AOPRM1OPRL1 | |
| SCHEMBL4004722 | 0.77 | SSTR4 (0.46) | SLC6A9SSTR4SCN9AOPRM1OPRL1 | |
| SCHEMBL4010688 | 0.76 | SSTR4 (0.46) | SLC6A9SSTR4SCN9AOPRM1OPRL1 | |
| SCHEMBL7314168 | 0.74 | SSTR4 (0.54) | SSTR4SCN9AOPRM1OPRL1 | |
| SCHEMBL4003526 | 0.74 | SSTR4 (0.45) | SLC6A9SSTR4SCN9AOPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778229-A4 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2009-06-17 | — | — | EP | disclosed |
| EP-1778229-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006020598-A2 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-02-23 | — | — | WO | disclosed |