Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | HPGDS | O60760 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | JAK1 | P23458 | 1/20 | 0.47 |
| ▸ | TYK2 | P29597 | 1/20 | 0.47 |
| ▸ | JAK3 | P52333 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20835999 | 0.86 | GPR119 (0.56) | GPR119POLBPDE10AKDM4EMAPT | |
| SCHEMBL6356443 | 0.86 | GPR119 (0.56) | GPR119POLBPDE10AKDM4EMAPT | |
| SCHEMBL15940947 | 0.86 | POLB (0.63) | GPR119POLBPDE10AKDM4EMAPT | |
| SCHEMBL31759156 | 0.85 | GPR119 (0.55) | GPR119POLBPDE10AKDM4EMAPT | |
| SCHEMBL17384582 | 0.85 | GPR119 (0.58) | GPR119POLBPDE10AJAK2JAK3 | |
| SCHEMBL2420888 | 0.84 | GPR119 (0.54) | GPR119POLBPDE10AKDM4EMAPT | |
| SCHEMBL19092624 | 0.84 | GPR119 (0.54) | GPR119POLBPDE10AKDM4EMAPT | |
| SCHEMBL19284734 | 0.84 | GPR119 (0.54) | GPR119POLBPDE10AKDM4EMAPT | |
| SCHEMBL19297055 | 0.83 | PDE10A (0.53) | GPR119POLBPDE10AKDM4EMAPT | |
| SCHEMBL2421222 | 0.83 | GPR119 (0.53) | GPR119POLBPDE10AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024046342-A1 | BENZO BICYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR, AND USE THEREOF | 广州市联瑞制药有限公司 | 2024-03-07 | — | — | WO | disclosed |
| WO-2009081259-A1 | PHENOXY-PYRIDYL DERIVATIVES | PFIZER INC. (US) | 2009-07-02 | — | — | WO | disclosed |
| WO-2009081259-A1 | PHENOXY-PYRIDYL DERIVATIVES | PFIZER INC. (US) | 2009-07-02 | — | — | WO | disclosed |