Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | SNCA | P37840 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4007081 | 1.00 | MEN1 (0.59) | MEN1NPC1RAB9AKMT2ASNCA | |
| SCHEMBL156861 | 0.86 | SNCA (0.64) | MEN1NPC1RAB9AKMT2ASNCA | |
| SCHEMBL61657 | 0.86 | SNCA (0.64) | MEN1NPC1RAB9AKMT2ASNCA | |
| SCHEMBL6421503 | 0.84 | SNCA (0.64) | MEN1NPC1RAB9AKMT2ASNCA | |
| SCHEMBL6421501 | 0.84 | SNCA (0.64) | MEN1NPC1RAB9AKMT2ASNCA | |
| SCHEMBL6492602 | 0.84 | MEN1 (0.59) | MEN1NPC1RAB9AKMT2ASNCA | |
| SCHEMBL708951 | 0.84 | NPC1 (0.63) | MEN1NPC1RAB9AKMT2ASNCA | |
| SCHEMBL6479879 | 0.84 | MEN1 (0.69) | MEN1NPC1RAB9AKMT2ASNCA | |
| SCHEMBL22360047 | 0.84 | MEN1 (0.63) | MEN1NPC1RAB9AKMT2ASNCA | |
| SCHEMBL6607138 | 0.84 | MEN1 (0.63) | MEN1NPC1RAB9AKMT2ASNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893245-A4 | RADIOLABELED-PEGYLATION OF LIGANDS FOR USE AS IMAGING AGENTS | UNIV PENNSYLVANIA (US) | 2009-06-24 | — | — | EP | disclosed |
| EP-1893245-A2 | RADIOLABELED-PEGYLATION OF LIGANDS FOR USE AS IMAGING AGENTS | The Trustees of the University of Pennsylvania (US) | 2008-03-05 | — | — | EP | disclosed |
| US-20070031328-A1 | Radiolabeled-pegylation of ligands for use as imaging agents | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2007-02-08 | — | — | US | disclosed |
| WO-2007002540-A2 | RADIOLABELED-PEGYLATION OF LIGANDS FOR USE AS IMAGING AGENTS | KUNG HANK F (US) | 2007-01-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070031328-A1 | Radiolabeled-pegylation of ligands for use as imaging agents | EGFR, LANCL1, FLT1 | MEN1 1380/4885NPC1 935/4885RAB9A 1417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.