SCHEMBL61657

SCHEMBL61657

C(=Cc1nc2ccccc2o1)c1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SNCA P37840 1/20 0.64
ELANE P08246 1/20 0.63
MEN1 O00255 3/20 0.61
NPC1 O15118 3/20 0.61
RAB9A P51151 3/20 0.61
KMT2A Q03164 3/20 0.61
HDAC3 O15379 1/20 0.59
HDAC4 P56524 1/20 0.59
HDAC1 Q13547 1/20 0.59
HDAC7 Q8WUI4 1/20 0.59
HDAC2 Q92769 1/20 0.59
HDAC10 Q969S8 1/20 0.59
HDAC11 Q96DB2 1/20 0.59
HDAC8 Q9BY41 1/20 0.59
HDAC6 Q9UBN7 1/20 0.59
HDAC9 Q9UKV0 1/20 0.59
HDAC5 Q9UQL6 1/20 0.59
KDM4E B2RXH2 2/20 0.54
ALDH1A1 P00352 2/20 0.54
HPGD P15428 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL156861 1.00 SNCA (0.64) SNCAELANEMEN1NPC1RAB9A
SCHEMBL6421501 0.90 SNCA (0.64) SNCAELANEMEN1NPC1RAB9A
SCHEMBL6421503 0.90 SNCA (0.64) SNCAELANEMEN1NPC1RAB9A
SCHEMBL6607138 0.86 MEN1 (0.63) SNCAELANEMEN1NPC1RAB9A
SCHEMBL4007081 0.86 MEN1 (0.59) SNCAMEN1NPC1RAB9AKMT2A
SCHEMBL708951 0.86 NPC1 (0.63) SNCAMEN1NPC1RAB9AKMT2A
SCHEMBL4007077 0.86 MEN1 (0.59) SNCAMEN1NPC1RAB9AKMT2A
SCHEMBL22360047 0.86 MEN1 (0.63) SNCAMEN1NPC1RAB9AKMT2A
SCHEMBL6479879 0.86 MEN1 (0.69) SNCAMEN1NPC1RAB9AKMT2A
SCHEMBL6492602 0.86 MEN1 (0.59) SNCAMEN1NPC1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 434 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110117262-B 2-styryl benzoxazole or benzothiazolyl ketoxime ester compound and preparation method and application thereof 同济大学 2023-04-11 CN claimed
CN-112266500-B Marking powder, preparation method and application thereof, high-rigidity PC alloy suitable for laser marking and preparation method thereof 万华化学(四川)有限公司 2022-03-11 CN claimed
CN-112266500-A Marking powder, preparation method and application thereof, high-rigidity PC alloy suitable for laser marking and preparation method thereof 万华化学(四川)有限公司 2021-01-26 CN claimed
CN-110117262-A 2- styryl benzoxazoles or benzothiazolyl ketoxime ester compound and its preparation method and application 同济大学 2019-08-13 CN claimed
US-10036124-B2 Separated treatment of paper substrate with multivalent metal salts and OBAs INTERNATIONAL PAPER COMPANY (US) 2018-07-31 US claimed
EP-2948185-B1 VECTORISED MAGNETIC EMULSION GUERBET SA (FR) 2018-03-07 EP claimed
EP-2654802-B1 CHELATE NANOEMULSION FOR MRI GUERBET SA (FR) 2017-12-06 EP claimed
US-9770520-B2 Chelate nanoemulsion for MRI GUERBET (FR) 2017-09-26 US claimed
US-20170037578-A1 SEPARATED TREATMENT OF PAPER SUBSTRATE WITH MULTIVALENT METAL SALTS AND OBAs INTERNATIONAL PAPER COMPANY (US) 2017-02-09 US claimed
EP-2948185-A1 VECTORISED MAGNETIC EMULSION Guerbet (FR) 2015-12-02 EP claimed
EP-0697481-A2 Aqueous textile treatment compositions containing an ultra-violet absorbing agent CIBA-GEIGY AG (CH) 1996-02-21 EP claimed
EP-0682145-A2 Textile treatment CIBA-GEIGY AG (CH) 1995-11-15 EP claimed
US-5269815-A Process for the fluorescent whitening of hydrophobic textile material with disperse fluorescent whitening agents from super-critical carbon dioxide CIBA-GEIGY CORPORATION (US) 1993-12-14 US claimed
US-5152922-A 1,4-DISTYRYLBENZENE COMPOUNDS AND MIXTURES THEREOF WITH OTHER 1,4-DISTYRYBENZENE COMPOUNDS CIBA-GEIGY CORPORATION (US) 1992-10-06 US claimed
EP-0136259-B1 4-HETEROCYCLYL-VINYL-4'-STYRYL-BIPHENYLS CIBA-GEIGY AG (CH) 1988-06-15 EP claimed
US-4666627-A FLUORESCENT BRIGHTENERS CIBA-GEIGY CORPORATION (US) 1987-05-19 US claimed
EP-0006271-B2 WASHING AND SOFTENING COMPOSITIONS CONTAINING NONIONIC BRIGHTENER THE PROCTER & GAMBLE COMPANY (US) 1986-01-22 EP claimed
EP-0136259-A1 4-Heterocyclyl-vinyl-4'-styryl-biphenyls CIBA-GEIGY AG (CH) 1985-04-03 EP claimed
EP-0006271-B1 WASHING AND SOFTENING COMPOSITIONS CONTAINING NONIONIC BRIGHTENER THE PROCTER & GAMBLE COMPANY (US) 1982-03-31 EP claimed
EP-0006271-A1 Washing and softening compositions containing nonionic brightener THE PROCTER & GAMBLE COMPANY (US) 1980-01-09 EP claimed