Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.56 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MMP14 | P50281 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1396014 | 0.91 | CYP3A4 (0.65) | CYP3A4MMP9MMP8MMP14RECQL | |
| Sulfuric Acid SCHEMBL124927 | 0.89 | CYP3A4 (0.54) | CYP3A4MMP9MMP8MMP14RECQL | |
| Sulfuric Acid SCHEMBL25300462 | 0.88 | RECQL (0.55) | CYP3A4MMP9MMP8MMP14RECQL | |
| Sulfuric Acid SCHEMBL4925238 | 0.87 | CYP3A4 (0.56) | CYP3A4MMP9MMP8MMP14RECQL | |
| Sulfuric Acid SCHEMBL28669372 | 0.86 | RECQL (0.54) | CYP3A4MMP9MMP8MMP14RECQL | |
| Sulfuric Acid SCHEMBL30386330 | 0.86 | RECQL (0.54) | CYP3A4MMP9MMP8MMP14RECQL | |
| Sulfuric Acid SCHEMBL4916289 | 0.84 | CYP3A4 (0.53) | CYP3A4MMP9MMP8MMP14RECQL | |
| Sulfuric Acid SCHEMBL4920694 | 0.84 | CYP3A4 (0.53) | CYP3A4MMP9MMP8MMP14RECQL | |
| Sulfuric Acid SCHEMBL4925304 | 0.84 | CYP3A4 (0.53) | CYP3A4MMP9MMP8MMP14RECQL | |
| Sulfuric Acid SCHEMBL4925474 | 0.84 | CYP3A4 (0.53) | CYP3A4MMP9MMP8MMP14RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1834766-B1 | Lithographic printing plate precursor | FUJIFILM CORP (JP) | 2009-06-17 | — | — | EP | disclosed |
| EP-1834766-A2 | Lithographic printing plate precursor | FUJIFILM Corporation (JP) | 2007-09-19 | — | — | EP | disclosed |